CellROX™ Reagent Variety Pack, for oxidative stress detection
CellROX™ Reagent Variety Pack, for oxidative stress detection
Invitrogen™

CellROX™ Reagent Variety Pack, for oxidative stress detection

The CellROX™ Variety Pack contains one vial (50 μL) each of CellROX™ Green Reagent, CellROX™ Orange Reagent, and CellROX™ DeepRead more
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Catalog NumberQuantity
C104481 kit
Catalog number C10448
Price (KRW)
629,000
Online offer
Ends: 31-Dec-2025
740,000
Save 111,000 (15%)
Each
Add to cart
Quantity:
1 kit
Price (KRW)
629,000
Online offer
Ends: 31-Dec-2025
740,000
Save 111,000 (15%)
Each
Add to cart
The CellROX™ Variety Pack contains one vial (50 μL) each of CellROX™ Green Reagent, CellROX™ Orange Reagent, and CellROX™ Deep Red Reagent. These reagents are novel fluorogenic probes for measuring cellular oxidative stress in live cells. These cell-permeant dyes exhibit bright fluorescence upon oxidation by reactive oxygen species (ROS). (See table below for details of each reagent.)

The CellROX™ reagents are:

• Optimized for detection of oxidative stress in live cells and may be added directly to serum-containing growth media
• Provided as a stable, ready-to-use DMSO solutions with simple protocols, compatible with standard workflows in fluorescence microscopy
• Compatible with a variety of detection platforms, including traditional fluorescence microscopy, high content screening (HCS), and flow cytometry

Oxidative stress results from an imbalance between the production of reactive oxygen species (ROS) and the ability of cells to scavenge them. ROS play an important role in the progression of several diseases, including inflammation, atherosclerosis, aging, and age-related degenerative disorders.

 Catalog # Absorption/Emission (Color) Live cell compatible? Formaldehyde fixable?Detergent resistant? Platforms
CellROX™ Deep Red ReagentC10422 644/665 nm (Deep Red) Yes YesNo Imaging, HCS, HTS, flow cytometry, Attune™
CellROX™ Orange ReagentC10443 545/565 nm (Orange) Yes NoNo Imaging, HCS, flow cytometry, Tali™
CellROX™ Green ReagentC10444 485/520 nm (Green) Yes YesYes Imaging, HCS, HTS, FLOW, Tali™, FLoid™, Attune™


For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
ColorOrange, Far-Red, Green
FormatFrozen
Quantity1 kit
Unit SizeEach

Frequently asked questions (FAQs)

What dyes can I use to detect reactive oxygen species (ROS) in my bacteria?

Many dyes that are used on mammalian cells have also been shown to be useful in bacterial cells. For example, CellROX Deep Red Reagent has been shown to work in B. subtilis (see Reference: http://www-brs.ub.ruhr-uni-bochum.de/netahtml/HSS/Diss/RaatschenNadja/diss.pdf). If you are interested in a particular dye, but are not sure if it will work on your bacteria, literature searches are the best way to check to see if it has been tested. If not, then it may be worth testing yourself.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

Citations & References (15)

Citations & References
Abstract
Mechanisms of programmed cell death signaling in hair cells and support cells post-electrode insertion trauma.
Authors:Eshraghi AA, Lang DM, Roell J, Van De Water TR, Garnham C, Rodrigues H, Guardiola M, Gupta C, Mittal J,
Journal:
PubMed ID:25761716
'Programmed cell death (PCD) initially starts in the support cells (SCs) after electrode insertion trauma (EIT), followed by PCD in hair cells (HCs). Activation of caspase-3 was observed only in SCs. Protecting both SCs and HCs with selective otoprotective drugs at an early stage post implantation may help to preserve ... More
Dynamics of sub-lethal effects of nano-CuO on the microalga Chlamydomonas reinhardtii during short-term exposure.
Authors:von Moos N, Maillard L, Slaveykova VI,
Journal:
PubMed ID:25731685
Though nano-CuO has been classified as toxic toward aquatic microorganisms and its use in various applications is expected to increase in near future, its ecotoxicity is currently poorly understood. The aim of this study was to investigate the mechanisms of nano-CuO toxicity based on the paradigm of oxidative stress, the ... More
Development of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications.
Authors:Shubin AD, Felong T, Graunke D, Ovitt CE, Benoit D,
Journal:
PubMed ID:25762214
Over 40,000 patients are diagnosed with head and neck cancers annually in the US with the vast majority receiving radiation therapy. Salivary glands are irreparably damaged by radiation therapy resulting in xerostomia, which severely affects patient quality of life. Cell-based therapies have shown some promise in mouse models of radiation-induced ... More
Oxidative stress triggers cytokinesis failure in hepatocytes upon isolation.
Authors:Tormos AM, Taléns-Visconti R, Bonora-Centelles A, Pérez S, Sastre J,
Journal:
PubMed ID:25744598
Primary hepatocytes are highly differentiated cells and proliferatively quiescent. However, the stress produced during liver digestion seems to activate cell cycle entry by proliferative/dedifferentiation programs that still remain unclear. The aim of this work was to assess whether the oxidative stress associated with hepatocyte isolation affects cell cycle and particularly ... More
DNA Damage: A Sensible Mediator of the Differentiation Decision in Hematopoietic Stem Cells and in Leukemia.
Authors:Weiss CN, Ito K,
Journal:
PubMed ID:25789504
In the adult, the source of functionally diverse, mature blood cells are hematopoietic stem cells, a rare population of quiescent cells that reside in the bone marrow niche. Like stem cells in other tissues, hematopoietic stem cells are defined by their ability to self-renew, in order to maintain the stem ... More