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Citations & References (31)
Invitrogen™
β-BODIPY™ FL C12-HPC (2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoyl)-1-Hexadecanoyl-sn-Glycero-3-Phosphocholine)
The intensely fluorescent BODIPY® (4,4-difluoro-3a,4a-diaza-s-indacene) fluorophore is intrinsically lipophilic, unlikemost other long-wavelength dyes. Consequently, probes incorporating this fluorophore are moreRead more
| Catalog Number | Quantity |
|---|---|
| D3792 | 100 μg |
Catalog number D3792
Price (KRW)
223,000
Online offer
Ends: 31-Dec-2025
262,000Save 39,000 (15%)
Each
Quantity:
100 μg
Price (KRW)
223,000
Online offer
Ends: 31-Dec-2025
262,000Save 39,000 (15%)
Each
The intensely fluorescent BODIPY® (4,4-difluoro-3a,4a-diaza-s-indacene) fluorophore is intrinsically lipophilic, unlikemost other long-wavelength dyes. Consequently, probes incorporating this fluorophore are more likely to mimic the properties of natural lipids. BODIPY® fatty acid analogs like BODIPY® 500/510 dodecanoic acid (D-3823) and BODIPY FL dodecanoic acid (D-3822) undergo native-like transport and metabolism in cells. They are therefore effective tracers of lipid trafficking, as well as being useful general-purpose membrane probes.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical Name or MaterialPhospholipids
Recommended StorageStore in freezer (-5 to -30°C) and protect from light.
Physical FormSolid
Product LineBODIPY
Quantity100 μg
Unit SizeEach
Citations & References (31)
Citations & References
Abstract
Separation and characterization of late endosomal membrane domains.
Journal:J Biol Chem
PubMed ID:12065580
'Very little is known about the biophysical properties and the lipid or protein composition of membrane domains presumably present in endocytic and biosynthetic organelles. Here we analyzed the membrane composition of late endosomes by suborganellar fractionation in the absence of detergent. We found that the internal membranes of this multivesicular
Multidrug transporter activity in lymphocytes.
Journal:Br J Pharmacol
PubMed ID:15492020
'Multidrug transporters play a dual role in haematopoietic cells, mediating the efflux of xenobiotics and regulating cell migration. For several reasons including the lack of specific antibodies, reports of multidrug transporter distribution on lymphocytes conflict. Murine B cells have been reported to completely lack transporter activity. Through analysis of parental
gamma-cyclodextrins greatly enhance translocation of hydrophobic fluorescent phospholipids from vesicles to cells in culture. Importance of molecular hydrophobicity in phospholipid trafficking studies.
Journal:J Biol Chem
PubMed ID:10585403
'Short-chain, fluorescent derivatives are commonly used to investigate intracellular phospholipid trafficking. However, their use can yield misleading results because they, unlike the native species, can rapidly distribute between organelles due to their low hydrophobicity. On the other hand, hydrophobic derivatives are very difficult to introduce to cells and thus have
Fluorescent membrane probes incorporating dipyrrometheneboron difluoride fluorophores.
Journal:Anal Biochem
PubMed ID:1799206
'The spectroscopic properties of a new series of fatty acid analogs in which a dipyrrometheneboron difluoride fluorophore forms a segment of the acyl methylene chain are presented and their characteristics as fluorescent membrane probes are examined. When incorporated as a low mole fraction component in model phospholipid membranes, the probes
Intracellular surfactant removal from phagocytized minerals: development of a fluorescent method using a BODIPY-labeled phospholipid.
Journal:Inhal Toxicol
PubMed ID:10880156
'Lung surfactant serves as a protective coating when adsorbed on particle surfaces, so its removal or rate of removal in vivo may affect expression of mineral cytotoxicity. Removal of phospholipid surfactant components from the surface of mineral particles ingested by alveolar macrophages (AM) was measured using fluorescence microscopy. Dipalmitoylphosphatidylcholine with