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인용 및 참조 문헌 (7)
Thermo Scientific™
GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)
Thermo Scientific Pierce GMBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| 22309 | 50 mg |
카탈로그 번호 22309
제품 가격(KRW)
244,000
온라인 행사
Ends: 31-Dec-2025
286,000할인액 42,000 (15%)
Each
수량:
50 mg
제품 가격(KRW)
244,000
온라인 행사
Ends: 31-Dec-2025
286,000할인액 42,000 (15%)
Each
Thermo Scientific Pierce GMBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).
Features of GMBS:
• Reactive groups: NHS ester and maleimide
• Reactive toward: amino and sulfhydryl groups
• C4-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
• NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
• Maleimides react with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-GMBS
• Short aliphatic spacer has low potential for eliciting an immune response
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Features of GMBS:
• Reactive groups: NHS ester and maleimide
• Reactive toward: amino and sulfhydryl groups
• C4-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
• NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
• Maleimides react with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-GMBS
• Short aliphatic spacer has low potential for eliciting an immune response
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성Yes
설명GMBS
형태Powder
라벨링 방법Chemical Labeling
분자량280.23
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide, NHS Ester
배송 조건Ambient
용해도DMF, DMSO
스페이서 암 길이7.3 Å
수용성No
화학물질 반응성Amine-Sulfhydryl
CleavableNo
교차결합제 유형Heterobifunctional
형식Standard
제품 유형Crosslinker
스페이서Short (<10 Å)
Unit SizeEach
구성 및 보관
Upon receipt store desiccated at 4°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)?
인용 및 참조 문헌 (7)
인용 및 참조 문헌
Abstract
Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms.
Journal:Nucleic Acids Res
PubMed ID:11024189
Different chemical methods used to attach oligonucleotides by their 5'-end on a glass surface were tested in the framework of solid phase PCR where surface-bound instead of freely-diffusing primers are used to amplify DNA. Each method was first evaluated for its capacity to provide a high surface coverage of oligonucleotides
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film
Recognition of galactan components of pectin by galectin-3.
Journal:FASEB J
PubMed ID:18832596
It has been reported that modified forms of pectin possess anticancer activity. To account for this bioactivity, it has been proposed that fragments of pectin molecules can act by binding to and inhibiting the various roles of the mammalian protein galectin 3 (Gal3) in cancer progression and metastasis. Despite this
Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.
Journal:Blood
PubMed ID:21427291
Aged or damaged RBCs are effectively removed from the blood circulation by Kupffer cells in the liver, but little is known regarding the mechanism of the clearance process. Here we show that stabilin-1 and stabilin-2 in hepatic sinusoidal endothelial cells (HSECs) are critical in effectively clearing damaged RBCs in mouse
Mapping specific adhesive interactions on living human intestinal epithelial cells with atomic force microscopy.
Journal:FASEB J
PubMed ID:18263697
Specific molecular-receptor interactions with gut epithelium cells are important in understanding bioactivity of food components and drugs, binding of commensal microflora, attachment and initiation of defense mechanisms against pathogenic bacteria and for development of targeted delivery systems to the gut. However, methods for probing such interactions are lacking. Methodology has