Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a자세히 알아보기
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카탈로그 번호
수량
22311
50 mg
카탈로그 번호 22311
제품 가격(KRW)
142,000
Online offer
Ends: 31-Dec-2025
167,000
할인액 25,000 (15%)
Each
카트에 추가하기
수량:
50 mg
제품 가격(KRW)
142,000
Online offer
Ends: 31-Dec-2025
167,000
할인액 25,000 (15%)
Each
카트에 추가하기
Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
Features of MBS:
• Reactive groups: NHS ester and maleimide • Reactive towards: amino and sulfhydryl groups • Non-cleavable • Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-MBS • Popular for forming enzyme immunoconjugates
Product References: Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성Yes
설명MBS
형태Powder
라벨링 방법Chemical Labeling
분자량314.25
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide, NHS Ester
배송 조건Ambient
용해도DMF, DMSO
스페이서 암 길이7.3 Å
수용성No
화학물질 반응성Amine-Sulfhydryl
CleavableNo
교차결합제 유형Heterobifunctional
형식Standard
제품 유형Crosslinker
스페이서Short (<10 Å)
Unit SizeEach
구성 및 보관
Upon receipt store desiccated at 4°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for MBS (m-maleimidobenzoyl-N-hydroxysuccinimide ester)?
MBS (m-maleimidobenzoyl-N-hydroxysuccinimide ester) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.
Different chemical methods used to attach oligonucleotides by their 5'-end on a glass surface were tested in the framework of solid phase PCR where surface-bound instead of freely-diffusing primers are used to amplify DNA. Each method was first evaluated for its capacity to provide a high surface coverage of oligonucleotides ... More
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Authors:Chrisey LA, Lee GU, O'Ferrall CE
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film ... More
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents.
Authors:Chen Z, Stokes DL, Rice WJ, Jones LR
Journal:J Biol Chem
PubMed ID:12972413
Heterobifunctional thiol to amine cross-linking agents were used to gain new insights on the dynamics and conformational factors governing the interaction between the cardiac Ca2+ pump (SERCA2a) and phospholamban (PLB). PLB is a small protein inhibitor of SERCA2a that reduces enzyme affinity for Ca2+ and thereby regulates cardiac contractility. We ... More