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인용 및 참조 문헌 (4)
Thermo Scientific™
SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
Thermo Scientific Pierce SMPB is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| 22416 | 50 mg |
카탈로그 번호 22416
제품 가격(KRW)
282,000
Online offer
Ends: 31-Dec-2025
331,000할인액 49,000 (15%)
Each
수량:
50 mg
제품 가격(KRW)
282,000
Online offer
Ends: 31-Dec-2025
331,000할인액 49,000 (15%)
Each
Thermo Scientific Pierce SMPB is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length aromatic spacer arm (11.6 angstroms).
Features of SMPB:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Extended chain analog of MBS
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Conjugates formed with SMPB are more stable in serum than SPDP conjugates
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
본 제품은 냉장/냉동제품으로 반송된 제품은 전량 폐기 처리 되오니 주문 전 상세 내용 다시 한번 확인 부탁드립니다.
Features of SMPB:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Extended chain analog of MBS
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Conjugates formed with SMPB are more stable in serum than SPDP conjugates
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
본 제품은 냉장/냉동제품으로 반송된 제품은 전량 폐기 처리 되오니 주문 전 상세 내용 다시 한번 확인 부탁드립니다.
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성Yes
설명SMPB
형태Powder
라벨링 방법Chemical Labeling
분자량356.33
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide, NHS Ester
배송 조건Ambient
용해도DMF, DMSO
스페이서 암 길이11.6 Å
수용성No
화학물질 반응성Amine-Sulfhydryl
CleavableNo
교차결합제 유형Heterobifunctional
형식Standard
제품 유형Crosslinker
스페이서Medium (10 to 30 Å)
Unit SizeEach
구성 및 보관
Upon receipt store desiccated at 4°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)?
인용 및 참조 문헌 (4)
인용 및 참조 문헌
Abstract
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film
Decorin is a novel antagonistic ligand of the Met receptor.
Journal:J Cell Biol
PubMed ID:19433454
'Decorin, a member of the small leucine-rich proteoglycan gene family, impedes tumor cell growth by down-regulating the epidermal growth factor receptor. Decorin has a complex binding repertoire, thus, we predicted that decorin would modulate the bioactivity of other tyrosine kinase receptors. We discovered that decorin binds directly and with high
Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.
Journal:J Immunol
PubMed ID:20483724
The levels of expression of alternatively spliced variants of CTLA-4 and insufficient CTLA-4 signaling have been implicated in type 1 diabetes. Hence, we hypothesized that increasing CTLA-4-specific ligand strength on autoantigen-presenting dendritic cells (DCs) can enhance ligation of CTLA-4 on T cells and lead to modulation of autoreactive T cell
Visualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor.
Journal:J Cell Sci
PubMed ID:21172803
Mechanical forces are ubiquitous modulators of cell activity but little is known about the mechanical stresses in the cell. Genetically encoded FRET-based force sensors now allow the measurement of local stress in specific host proteins in vivo in real time. For a minimally invasive probe, we designed one with a