iPrPAC-dG Phosphoramidite, standard grade, serum vial bottle

The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions. Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05M potassium carbonate in methanol. The 'Standard Grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems∣AKTA Systems of oligonucleotide synthesizers.

Features:

• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isopropylphenoxyacetyl-2'-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C₅₁H₆₀N₇O₉P
• Base—dG
• Base Protection—iPrPAC
• Formula weight—946.05 g/mol
• CAS number—150065-82-0
• HPLC Purity—≥98.0%
• 31P NMR Purity—≥98.0%