GlutaMAX™ Supplement

Gibco™ GlutaMAX™ Supplement is an alternative to L-glutamine, with increased stability that improves cell health. GlutaMAX™ Supplement is suitable for both adherent and suspension culture of mammalian cells, with no adaptation required. GlutaMAX™ Supplement is offered as a 200 mM L-alanyl-L-glutamine dipeptide in 0.85% NaCl. GlutaMAX™ Supplement is also included in a variety of media formulations. Compared to L-glutamine, GlutaMAX™ Supplement:

• Minimizes toxic ammonia build-up
• Improves cell viability and growth
• Remains stable across a wide range of temperatures

Minimizes Toxic Ammonia Build-up
Unlike L-glutamine, GlutaMAX™ Supplement does not spontaneously break down to form ammonia. Instead, cells cleave the dipeptide bond to release L-glutamine as needed. This system prevents waste build-up and maintains a fresh supply of L-glutamine during long-term culture.

Improves Cell Viability and Growth
Cultures with lower levels of ammonia show improved cell viability. In addition, culture conditions are more controlled due to the consistent concentration of GlutaMAX™ Supplement that is not possible with L-glutamine.

Remains Stable Across a Wide Range of Temperatures
GlutaMAX™ Supplement is room-temperature stable and ready to use. GlutaMAX™ Supplement retains full functionality for 24 months at room temperature, 2 to 8°C, or -5 to -30°C for convenient storage and handling. GlutaMAX™ Supplement is even stable at 37°C for a week or more.

cGMP Manufacturing and Quality System
Gibco™ GlutaMAX™ supplement is manufactured at a cGMP compliant facility, located in Paisley, Scotland. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standard. For supply chain continuity, Life Technologies offers an identical Gibco™ GlutaMAX™ supplement made in our Grand Island, New York facility (35050-061). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standards.