Axiom™ Ovine Genotyping Array (50K)

The Applied Biosystems Axiom Ovine Genotyping Array (50K) provides the power and resolution to enable a wide range of applications in sheep breeding, including breed assignment, parentage verification and discovery, and traceability and monitoring of polymorphisms of known large effect. The Axiom Ovine Genotyping Array includes markers that were selected by the International Sheep Genomics Consortium, with markers derived from three separate sequencing experiments. The array content is augmented with additional markers for parentage testing and traceability in globally diverse breeds of sheep. These include 163 highly informative parentage markers (MAF ≥0.3) in 48 +5 breed groups that enable accurate parentage testing and traceability in many of the world’s sheep breeds.

Features include:
• Expert design—developed in collaboration with Donagh Berry at Teagasc, Animal and Grassland Research and Innovation Center, Ireland
• Exceptionally high quality SNPs with excellent call and concordance rates across platforms and laboratories
• Includes SNPs for parentage as well as other traits including scrapie
• Compatible with Sheep Consortium 15K arrays and thus with previous studies

Applications
• Parentage verification and discovery
• Accurate genomic evaluations
• Genome-wide associations following accurate imputation to higher density panel
• Breed assignment
• Monitoring of major genes
• Aneuploidy detection—early detection of such abnormalities enables identification of animals that are not suitable parents for the next generation
• Measurement of genetic diversity including calculation of genomic inbreeding statistics
• Mating designs
• Traceability

Data from the Axiom Ovine Genotyping Array are analyzed using Axiom Analysis Suite and Axiom CNV Summary Tools software. The data can also be exported into long format using the Axiom Long Format Export Tool (AxLE).

Required products
GeneChip Command Console Software
GeneTitan Multi-Channel Instrument
Axiom Analysis Suite Software