Axiom™ Pan-African Cancer Research Assay Kit, array 1

The Applied Biosystems Axiom Pan-African Cancer Research Assay Kit is comprised of two arrays (array 1 and array 2, sold separately) offering over 1.5 million markers and an imputation-aware GWAS grid that tags over 94% of variants commonly found in African populations. The kit enables better novel disease associations with prostate and other cancers for African populations as well as other 1000G super-populations and provides high coverage of whole genome common variants (minor allele frequency > 5%) and rare variants (MAF >1 %). For Axiom Pan-African Research Assay Kit (array 2), please see Cat. No. 952407. Features of the Axiom Pan-African Cancer Research Array include:
• Cancer research-related variants optimized for coverage in African populations while offering high coverage across all 1000G super-populations
• Two-array design: Array 1 offers 801,275 markers and Array 2 offers 790,170 markers covering common variants (MAF >5%) and rare variants (MAF >1%) in African populations Axiom Pan-African Cancer Research array 1 coverage includes:
• Over 526K GWAS grid variant markers for optimal whole-genome imputation targeting common variants (minor allele frequency >5%) and rare variants (MAF >1%)
• Over 81K variants associated with cancer susceptibility, including prostate, breast, colon, and other cancers
• 24,595 prostate expression quantitative loci’s (eQTLs)
• 38,649 markers from NHGRi database associated with variety of diseases and traits