The hapten, biotin azide is reactive with terminal alkynes via a copper-catalyzed click reaction. Biotin can be subsequently detected with자세히 알아보기
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카탈로그 번호
수량
B10184
1 mg
카탈로그 번호 B10184
제품 가격(KRW)
798,000
キャンペーン価格
Ends: 31-Dec-2025
886,000
할인액 88,000 (10%)
Each
카트에 추가하기
수량:
1 mg
제품 가격(KRW)
798,000
キャンペーン価格
Ends: 31-Dec-2025
886,000
할인액 88,000 (10%)
Each
카트에 추가하기
The hapten, biotin azide is reactive with terminal alkynes via a copper-catalyzed click reaction. Biotin can be subsequently detected with streptavidin, avidin or NeutrAvidin® biotin-binding protein.
For Research Use Only. Not for use in diagnostic procedures.
사양
화학물질 반응성Alkyne
형식Solid
라벨 또는 염료Biotin
분자량615.79 Da
제품 유형Biotin Azide
수량1 mg
반응성 그룹Azide
반응성 부분Amine, Azide
배송 조건Room Temperature
용해도DMSO (Dimethylsulfoxide)
색상None
라벨 유형Biotin and Other Haptens
제품라인Molecular Probes
Unit SizeEach
구성 및 보관
Store at ≤-20°C and keep desiccated.
인용 및 참조 문헌 (12)
인용 및 참조 문헌
Abstract
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.
Authors:Kobayashi M, Aida M, Nagaoka H, Begum NA, Kitawaki Y, Nakata M, Stanlie A, Doi T, Kato L, Okazaki IM, Shinkura R, Muramatsu M, Kinoshita K, Honjo T,
Journal:Proc Natl Acad Sci U S A
PubMed ID:20018730
'To initiate class switch recombination (CSR) activation-induced cytidine deaminase (AID) induces staggered nick cleavage in the S region, which lies 5'' to each Ig constant region gene and is rich in palindromic sequences. Topoisomerase 1 (Top1) controls the supercoiling of DNA by nicking, rotating, and religating one strand of DNA. ... More
Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.
Authors:Vila A, Tallman KA, Jacobs AT, Liebler DC, Porter NA, Marnett LJ,
Journal:Chem Res Toxicol
PubMed ID:18232660
'Polyunsaturated fatty acids (PUFA) are primary targets of free radical damage during oxidative stress. Diffusible electrophilic alpha,beta-unsaturated aldehydes, such as 4-hydroxynonenal (HNE), have been shown to modify proteins that mediate cell signaling (e.g., IKK and Keap1) and alter gene expression pathways responsible for inducing antioxidant genes, heat shock proteins, and ... More
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.
Authors:Luebben SW, Kawabata T, Johnson CS, O'Sullivan MG, Shima N,
Journal:
PubMed ID:24589582
'Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway in a tumor-prone mouse model (Mcm4(chaos3)) with a ... More
Metabolic labeling of sialic acids in living animals with alkynyl sugars.
Authors:Chang PV, Chen X, Smyrniotis C, Xenakis A, Hu T, Bertozzi CR, Wu P,
Journal:Angew Chem Int Ed Engl
PubMed ID:19388017
Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living ... More
Regulation of the Skeletal Muscle Ryanodine Receptor/Ca2+-release Channel RyR1 by S-Palmitoylation.
Authors:Chaube R, Hess DT, Wang YJ, Plummer B, Sun QA, Laurita K, Stamler JS,
Journal:
PubMed ID:24509862
The ryanodine receptor/Ca(2+)-release channels (RyRs) of skeletal and cardiac muscle are essential for Ca(2+) release from the sarcoplasmic reticulum that mediates excitation-contraction coupling. It has been shown that RyR activity is regulated by dynamic post-translational modifications of Cys residues, in particular S-nitrosylation and S-oxidation. Here we show that the predominant ... More