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인용 및 참조 문헌 (23)
Invitrogen™
DQ™ Ovalbumin - Special Packaging
DQ ovalbumin is a fluorogenic substrate for proteases. A strong fluorescence quenching effect is observed when proteins are heavily labeled자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| D12053 | 5 x 1 mg |
카탈로그 번호 D12053
제품 가격(KRW)
702,000
Online offer
Ends: 31-Mar-2026
802,000할인액 100,000 (12%)
Each
수량:
5 x 1 mg
제품 가격(KRW)
702,000
Online offer
Ends: 31-Mar-2026
802,000할인액 100,000 (12%)
Each
DQ ovalbumin is a fluorogenic substrate for proteases. A strong fluorescence quenching effect is observed when proteins are heavily labeled with BODIPY dyes. Upon hydrolysis of the DQ ovalbumin to single, dye-labeled peptides by proteases, this quenching is relieved, producing brightly fluorescent products.
For Research Use Only. Not for use in diagnostic procedures.
사양
라벨 또는 염료BODIPY™ FL
제품라인DQ
제품 유형Antigen processing and presentation studies
수량5 x 1 mg
배송 조건Room Temperature
기질Protease Substrate
검출 방법Fluorescence
형태Solid
Substrate PropertiesProtein-Based Substrate
Target EnzymeProteases
Unit SizeEach
구성 및 보관
Store in freezer (-5 to -30°C) and protect from light.
자주 묻는 질문(FAQ)
Do you have an alternative for DQ Ovalbumin – Special Packaging (Cat. No. D12053) that can be purchased in the EU?
인용 및 참조 문헌 (23)
인용 및 참조 문헌
Abstract
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Journal:Nat Immunol
PubMed ID:14716310
'Microbial DNA sequences containing unmethylated CpG dinucleotides activate Toll-like receptor 9 (TLR9). We have found that TLR9 is localized to the endoplasmic reticulum (ER) of dendritic cells (DCs) and macrophages. Because there is no precedent for immune receptor signaling in the ER, we investigated how TLR9 is activated. We show
Carbohydrate oxidation acidifies endosomes, regulating antigen processing and TLR9 signaling.
Journal:J Immunol
PubMed ID:20200279
'Phagocytes kill encapsulated microbes through oxidative cleavage of surface carbohydrates, releasing glycan fragments and microbial contents that serve as ligands for immune receptors, which tailor the immune response against the offending pathogen. The glycan fragments serve as MHC class II (MHC II) ligands and innate receptor agonists, whereas microbial proteins
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Journal:Nat Immunol
PubMed ID:18604214
'Inhalation of silica crystals causes inflammation in the alveolar space. Prolonged exposure to silica can lead to the development of silicosis, an irreversible, fibrotic pulmonary disease. The mechanisms by which silica and other crystals activate immune cells are not well understood. Here we demonstrate that silica and aluminum salt crystals
Digestion assays in allergenicity assessment of transgenic proteins.
Journal:Environ Health Perspect
PubMed ID:16882518
'The food-allergy risk assessment for transgenic proteins expressed in crops is currently based on a weight-of-evidence approach that holistically considers multiple lines of evidence. This approach recognizes that no single test or property is known to distinguish allergens from nonallergens. The stability of a protein to digestion, as predicted by
Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients.
Journal:PLoS One
PubMed ID:20027300
'BACKGROUND: Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations in the CHM gene, which encodes Rab escort protein-1 (REP-1), an escort protein involved in the prenylation of Rabs. Under-prenylation of certain Rabs, as a result of loss of function mutations in REP-1, could affect vesicular trafficking, exocytosis and