Epidermal Growth Factor, Biotin-XX Conjugate (biotin EGF)
Epidermal Growth Factor, Biotin-XX Conjugate (biotin EGF)
인용 및 참조 문헌 (30)
Invitrogen™

Epidermal Growth Factor, Biotin-XX Conjugate (biotin EGF)

이 정제된 상피성장인자(epidermal growth factor, EGF)는 N 말단 아미노산에 단일 biotin-XX 분자를 가지고 있습니다. Biotin-XX EGF는 기존 보다 더 긴자세히 알아보기
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카탈로그 번호수량
E347720 μg
카탈로그 번호 E3477
제품 가격(KRW)
714,000
線上優惠
Ends: 31-Mar-2026
816,000
할인액 102,000 (13%)
Each
카트에 추가하기
수량:
20 μg
제품 가격(KRW)
714,000
線上優惠
Ends: 31-Mar-2026
816,000
할인액 102,000 (13%)
Each
카트에 추가하기
이 정제된 상피성장인자(epidermal growth factor, EGF)는 N 말단 아미노산에 단일 biotin-XX 분자를 가지고 있습니다. Biotin-XX EGF는 기존 보다 더 긴 잔기를 가지고 있어 EGF 수용체와의 결합력을 높이고 dye –streptavidin 분자, Qdot™ nanocrystals–streptavidin 분자, 효소-접합 streptavidin의 결합을 촉진합니다. 표지된 EGF를 사용해 과학자들은 수용체-막 (receptor-membrane) 상호작용과 수용체 분포를 연구하고 EGF와 수용체 상호작용의 반응속도 상수를 계산할 수 있습니다.

상피성장인자 사양:
• EGF 분자: 53 아미노산, MW=6,045 Da
• EGF 분자당 biotin-XX 분자수: 1

형광 EGF conjugate 찾기
Biotinylated EGF 외에 본사는 선택된 형광 streptavidin 표지에 사전 결합된 biotinylated EGF와 몇 가지 형광 dye로 직접 표지된 EGF를 제공합니다. 이들 제품에 대한 더 많은 정보는 Molecular Probes™ 핸드북에서 후속 수용체 결합 및 식세포 작용 probe—Section 16.1을 참조하십시오.

연구용으로만 사용할 수 있습니다. 사람이나 동물의 치료 또는 진단용으로 사용할 수 없습니다.
For Research Use Only. Not for use in diagnostic procedures.
사양
검출 방법Fluorescence
라벨 또는 염료Biotin & Other Haptens
수량20 μg
배송 조건Wet Ice
형태Solid
제품 유형Growth Factor
Unit SizeEach
구성 및 보관
Store in freezer (-5 to -30°C).

인용 및 참조 문헌 (30)

인용 및 참조 문헌
Abstract
Localization of EGF receptors in frozen tissue sections by antibody and biotinylated EGF-based techniques.
Authors:Reeves JR, Cooke TG, Fenton-Lee D, McNicol AM, Ozanne BW, Richards RC, Walsh A
Journal:J Histochem Cytochem
PubMed ID:8308248
'We developed a sensitive EGF receptor detection method for frozen tissue sections using biotinylated EGF as the primary reagent. The method was directly compared with an immunohistochemical technique based on an anti-EGF receptor monoclonal antibody (MAb EGFR1) in normal human and rat tissues and in human tumors. The method was ... More
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway.
Authors:Petiot A, Faure J, Stenmark H, Gruenberg J
Journal:J Cell Biol
PubMed ID:12975344
'While evidence is accumulating that phosphoinositide signaling plays a crucial role in growth factor and hormone receptor down-regulation, this signaling pathway has also been proposed to regulate endosomal membrane transport and multivesicular endosome biogenesis. Here, we have followed the fate of the down-regulated EGF receptor (EGFR) and bulk transport (fluid ... More
Retention of biologic activity of human epidermal growth factor following conjugation to a blood-brain barrier drug delivery vector via an extended poly(ethylene glycol) linker.
Authors:Deguchi Y, Kurihara A, Pardridge WM
Journal:Bioconjug Chem
PubMed ID:9893961
'Human brain gliomas overexpress the receptor for epidermal growth factor (EGF), and radiolabeled EGF is a potential peptide radiopharmaceutical for imaging human brain tumors, should this peptide be made transportable through the blood-brain barrier (BBB) in vivo. Peptide drug delivery to the brain may be facilitated by conjugating peptide radiopharmaceuticals ... More
In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic.
Authors:Stieber A, Mourelatos Z, Gonatas NK
Journal:Am J Pathol
PubMed ID:8579105
'Recent immunocytochemical and morphometric studies in amyotrophic lateral sclerosis, Alzheimer's disease (AD), and aging indicate that the neuronal Golgi apparatus is a reliable index of activity or degeneration. To further evaluate a possible role of the Golgi apparatus in the pathogenesis of AD, we examined by double labeling the neuronal ... More
Targeted cellular delivery of quantum dots loaded on and in biotinylated liposomes.
Authors:Sigot V, Arndt-Jovin DJ, Jovin TM,
Journal:Bioconjug Chem
PubMed ID:20715851
'We describe the preparation, biophysical characterization, and receptor-mediated cellular internalization of biotinylated lipid particles (BLPs) loaded on the surface and internally with two distinct (colors) of quantum dot (QD) probes. BLPs were formulated with 1.4 and 2.7 mol % PEG-lipids containing either a fusogenic or pH-sensitive lipid to promote bilayer ... More
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