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Gibco™
Cryopreserved Human Kupffer Cells
Cryopreserved Human Kupffer Cells are isolated from adult human livers. Each vial contains a minimum of one million viable cells.자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| HUKCCS | 1 vial |
카탈로그 번호 HUKCCS
제품 가격(KRW)
2,203,000
온라인 행사
Ends: 31-Mar-2026
2,447,000할인액 244,000 (10%)
Each
수량:
1 vial
제품 가격(KRW)
2,203,000
온라인 행사
Ends: 31-Mar-2026
2,447,000할인액 244,000 (10%)
Each
Cryopreserved Human Kupffer Cells are isolated from adult human livers. Each vial contains a minimum of one million viable cells. These easy-to-use cells provide a convenient way to produce hepatocyte and Kupffer cell co-cultures for the study of various hepatic functions.
• Viability routinely >90%
• Purity routinely >90%
• Respond to activation with lipopolysaccharides (LPS)
• Minimum 1 million viable cells per vial
• Protocols for hepatocyte co-culture available
Kupffer Cells Provide for Improved Physiological Modeling
Growing evidence shows that under both normal and pathological conditions, many hepatocyte functions are regulated by substances released from neighboring non-parenchymal cells (NPC). These cells, particularly Kupffer cells, play an important role in the modulation of xenobiotic metabolism in the liver. Kupffer cells secrete potent mediators of the inflammatory response that controls liver inflammation. These cytokine mediators control hepatocyte metabolic rates through direct interactions with phase I and phase II enzymes. Kupffer cell and hepatocyte co-cultures can self-assemble within 72 hours of treatment with pro-inflammatory cytokines or LPS, and can function by effectively modulating P450 expression, thus giving a more physiologically relevant result. Studies indicate that co-culture of hepatocytes with NPCs better represent both normal liver physiology as well as disease states.
• Viability routinely >90%
• Purity routinely >90%
• Respond to activation with lipopolysaccharides (LPS)
• Minimum 1 million viable cells per vial
• Protocols for hepatocyte co-culture available
Kupffer Cells Provide for Improved Physiological Modeling
Growing evidence shows that under both normal and pathological conditions, many hepatocyte functions are regulated by substances released from neighboring non-parenchymal cells (NPC). These cells, particularly Kupffer cells, play an important role in the modulation of xenobiotic metabolism in the liver. Kupffer cells secrete potent mediators of the inflammatory response that controls liver inflammation. These cytokine mediators control hepatocyte metabolic rates through direct interactions with phase I and phase II enzymes. Kupffer cell and hepatocyte co-cultures can self-assemble within 72 hours of treatment with pro-inflammatory cytokines or LPS, and can function by effectively modulating P450 expression, thus giving a more physiologically relevant result. Studies indicate that co-culture of hepatocytes with NPCs better represent both normal liver physiology as well as disease states.
For Research Use Only. Not for use in diagnostic procedures.
사양
공여자 소스Single Donor
셀 수1 x 106
제품 유형Human Kupffer Cell
수량1 vial
셀 유형Macrophage Cells
Culture TypeAdherent Cell Culture
형태Cryopreserved
종Human
Unit SizeEach
구성 및 보관
1 vial of 1 million viable human Kupffer cells.
Store in a cryostorage dewar or -135°C freezer.
Store in a cryostorage dewar or -135°C freezer.