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관련 제품 추천
The Tango™ CHRM2-bla U2OS cells contain the human Cholinergic muscarinic 2 receptor (CHRM2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ CHRM2-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Carbachol. In addition, Tango™ CHRM2-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
The Tango™ CHRM2-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Carbachol. In addition, Tango™ CHRM2-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.
사양
등록 번호
NM_000739.2
어세이 입력
Cell-based beta-arrestin recruitment
셀 상태
Dividing Cells
세포질 후미
Tail from GRPR GPCR
검출 방법
Fluorescent
유전자 기호
M2
개체군 상태
Single Cell Clone Origin
제품라인
Tango™
리포터 유전자
BLA (Beta-Lactamase)
배송 조건
Room Temperature
타겟 입력
CHRM2, M2
세포주
U2OS
System Type
Tango™
Druggable Target
GPCR
구성 및 보관
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
o Tango™ CHRM2-bla U2OS cells
o Tango™ CHRM2-bla U2OS Assay Protocol
o Certificate of Analysis
The Tango™ CHRM2-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Includes:
o Tango™ CHRM2-bla U2OS cells
o Tango™ CHRM2-bla U2OS Assay Protocol
o Certificate of Analysis
The Tango™ CHRM2-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
그림
문서 및 다운로드
Certificates | 증명서
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