LDS 751
LDS 751
Invitrogen™

LDS 751

LDS 751 is a cell-permeant nucleic acid stain that has a peak excitation at ∼543 nm on dsDNA and is자세히 알아보기
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카탈로그 번호수량
L759510 mg
카탈로그 번호 L7595
제품 가격(KRW)
312,000
Online offer
Ends: 31-Dec-2025
366,000
할인액 54,000 (15%)
Each
카트에 추가하기
수량:
10 mg
제품 가격(KRW)
312,000
Online offer
Ends: 31-Dec-2025
366,000
할인액 54,000 (15%)
Each
카트에 추가하기
LDS 751 is a cell-permeant nucleic acid stain that has a peak excitation at ∼543 nm on dsDNA and is particular useful in multicolor analyses due to its long wavelength emission maximum (∼712 nm). Binding of LDS 751 to dsDNA results in a ∼20-fold fluorescence enhancement.
For Research Use Only. Not for use in diagnostic procedures.
사양
검출 방법Fluorescence
염료 유형LDS 751
여기 파장 범위543⁄712
용도(장비)Flow Cytometer
형태Solid
수량10 mg
배송 조건Room Temperature
제품 유형Nucleic Acid Stain
SubCellular LocalizationNucleic Acids, Nucleus
Unit SizeEach
구성 및 보관
Contains 1 vial of LDS 751 (10 mg). Store at room temperature and protect from light.

인용 및 참조 문헌 (42)

인용 및 참조 문헌
Abstract
Dyes providing increased sensitivity in flow-cytometric dye-efflux assays for multidrug resistance.
Authors:Frey T, Yue S, Haugland RP
Journal:Cytometry
PubMed ID:7587707
In an effort to improve detection of P-glycoprotein-mediated multidrug resistance (mdr), several dyes were compared to rhodamine 123 (R123) in efflux assays. Two dyes (SY-38 and SY-3150) were found that provided better sensitivity. These dyes were effluxed by a cell line known to be mdr-positive (P388/R84) but not by an ... More
Modulation of platelet-neutrophil interaction with pharmacological inhibition of fibrinogen binding to platelet GPIIb/IIIa receptor.
Authors:Xiao Z, Théroux P, Frojmovic M
Journal:Thromb Haemost
PubMed ID:10064007
'The study investigated how drug inhibition of the GPIIb/IIIa receptor influences the interactions between platelets and leukocytes. These interactions are believed to play an important role in the etiology of the acute coronary syndromes. Thirty patients with unstable angina or non-Q-wave myocardial infarction were studied before the administration of tirofiban ... More
Discriminating between damaged and intact cells in fixed flow cytometric samples.
Authors:Terstappen LW, Shah VO, Conrad MP, Recktenwald D, Loken MR
Journal:Cytometry
PubMed ID:2460298
'A vital, nucleic acid stain (LDS-751) was used to discriminate intact from damaged cells in a flow cytometer even after the samples had been fixed with paraformaldehyde. Three major cell populations with different fluorescence properties with LDS-751 were found in the fixed samples. Cells not staining or only dimly staining ... More
The Q-Prep system: effects on the apparent expression of leucocyte cell surface antigens.
Authors:Macey MG, McCarthy DA, Davies C, Newland AC
Journal:Cytometry
PubMed ID:9149913
'To facilitate the analysis of immunolabelled peripheral blood or bone marrow leucocytes by flow cytometry, a number of reagents are available commercially that lyse erythrocytes and fix leucocytes. This study has investigated the effect on antibody-labelled whole blood of the Q-Prep procedure, in which erythrocytes are lysed with formic acid, ... More
Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs.
Authors:Lugo MR, Sharom FJ
Journal:Biochemistry
PubMed ID:16229491
'The P-glycoprotein efflux pump, an ABC superfamily member, can export a wide variety of hydrophobic drugs, natural products, and peptides from cells, powered by the energy of ATP hydrolysis. Transport substrates appear to first partition into the membrane and then interact with the protein within the cytoplasmic leaflet. Two drug ... More