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인용 및 참조 문헌 (57)
Invitrogen™
Methotrexate, Fluorescein, triammonium Salt (Fluorescein Methotrexate)
The green-fluorescent fluorescein methotrexate (absorption⁄emission maxima ∼496⁄516 nm) can be used to probe dihydrofolate reductase (DHFR) expression by fluorescence microscopy자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| M1198MP | 1 mg |
카탈로그 번호 M1198MP
제품 가격(KRW)
532,000
Online offer
Ends: 31-Dec-2025
625,000할인액 93,000 (15%)
Each
수량:
1 mg
제품 가격(KRW)
532,000
Online offer
Ends: 31-Dec-2025
625,000할인액 93,000 (15%)
Each
The green-fluorescent fluorescein methotrexate (absorption⁄emission maxima ∼496⁄516 nm) can be used to probe dihydrofolate reductase (DHFR) expression by fluorescence microscopy or flow cytometry.
For Research Use Only. Not for use in diagnostic procedures.
사양
라벨 유형Classic Dyes
분자식C46H54N14O9S
수량1 mg
권장 스토리지Store in freezer (-5°C to -30°C) and protect from light.
배송 조건Room Temperature
물리적 형태Solid
제품 유형Fluorescein Methotrexate
Unit SizeEach
인용 및 참조 문헌 (57)
인용 및 참조 문헌
Abstract
Xenobiotic transport across isolated brain microvessels studied by confocal microscopy.
Journal:Molecular pharmacology
PubMed ID:11093774
Visualization of membrane-associated folate transport proteins.
Journal:Adv Enzyme Regul
PubMed ID:2516406
'Transport of Methotrexate (MTX) into cells, via the "reduced folate" transport system, is a critical factor in the effectiveness of the drug in cancer chemotherapy, and defective transport is one of the principal types of resistance to MTX. Probes capable of detecting membrane-associated folate transport proteins (ftp''s) in individual cells
MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus).
Journal:Toxicol Sci
PubMed ID:17324950
'We used proximal tubules isolated from the killifish, Fundulus heteroclitus, to examine the effect of environmentally relevant, sublethal levels of arsenic on the function and expression of MRP2, an ABC transporter that transports xenobiotics into urine, including arsenic-glutathione conjugates. Exposure of fish to arsenic as sodium arsenite (4-14 days) increased
Characterization of a lipophilic antifolate resistance provoked by treatment of mammalian cells with the antiparasitic agent pyrimethamine.
Journal:J Biol Chem
PubMed ID:8440739
'We describe the characterization of an antitumor drug resistance following multiple step selection of hamster cells to the 2,4-diaminopyrimidines (DAP) metoprine, pyrimethamine (Pyr), and trimethoprim (Tmp). Pyr and Tmp are DAP lipophilic antifolates currently used as antiparasitic and antibacterial antibiotics, respectively. Dihydrofolate reductase (DHFR) from hamster cells bore a low
Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia.
Journal:Blood
PubMed ID:1381235
'Although the mechanisms of resistance to methotrexate (MTX) are known in experimental tumors made resistant to this drug, little information is available regarding acquired resistance to MTX in patients. A competitive displacement assay using the fluorescent lysine analogue of MTX, N-(4-amino-4-deoxy-N10-methylpteroyl)-N epsilon-(4''-fluorescein-thiocarbamyl)-L-lysine (PT430), was developed as a sensitive method of