SPQ (6-Methoxy-N-(3-Sulfopropyl)Quinolinium, Inner Salt)
SPQ (6-Methoxy-<i>N</i>-(3-Sulfopropyl)Quinolinium, Inner Salt)
Invitrogen™

SPQ (6-Methoxy-N-(3-Sulfopropyl)Quinolinium, Inner Salt)

The chloride indicator SPQ has absorption/emission maxima ∼344/443 and detects Cl- via diffusion-limited collisional quenching.Learn more about ion indicators including자세히 알아보기
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카탈로그 번호수량
M440100 mg
카탈로그 번호 M440
제품 가격(KRW)
314,000
온라인 행사
Ends: 31-Dec-2025
369,000
할인액 55,000 (15%)
Each
카트에 추가하기
수량:
100 mg
제품 가격(KRW)
314,000
온라인 행사
Ends: 31-Dec-2025
369,000
할인액 55,000 (15%)
Each
카트에 추가하기
The chloride indicator SPQ has absorption/emission maxima ∼344/443 and detects Cl- via diffusion-limited collisional quenching.

Learn more about ion indicators including calcium, potassium, pH, and membrane potential indicators ›

For Research Use Only. Not for use in diagnostic procedures.
사양
검출 방법Fluorescence
염료 유형Fluorescent Dye-Based
수량100 mg
배송 조건Room Temperature
용도 (장비)Confocal Microscope, Flow Cytometer
제품 유형Chloride Indicator
Unit SizeEach
구성 및 보관
Store at room temperature and protect from light.

인용 및 참조 문헌 (139)

인용 및 참조 문헌
Abstract
Identification by site-directed mutagenesis of three arginines in uncoupling protein that are essential for nucleotide binding and inhibition.
Authors:Modrianský M, Murdza-Inglis DL, Patel HV, Freeman KB, Garlid KD
Journal:J Biol Chem
PubMed ID:9312070
Primary regulation of uncoupling protein is mediated by purine nucleotides, which bind to the protein and allosterically inhibit fatty acid-induced proton transport. To gain increased understanding of nucleotide regulation, we evaluated the role of basic amino acid residues using site-directed mutagenesis. Mutant and wild-type proteins were expressed in yeast, purified, ... More
Fluorescent indicators of ion concentrations.
Authors:Tsien RY
Journal:Methods Cell Biol
PubMed ID:2538708
Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal.
Authors:Prince LS, Peter K, Hatton SR, Zaliauskiene L, Cotlin LF, Clancy JP, Marchase RB, Collawn JF
Journal:J Biol Chem
PubMed ID:9920908
'We previously demonstrated that the cystic fibrosis transmembrane conductance regulator (CFTR) is rapidly endocytosed in epithelial cells (Prince, L. S., Workman, R. B., Jr., and Marchase, R. B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5192-5196). To determine the structural features of CFTR required for endocytosis, we prepared ... More
Estimation of intracellular chloride activity in isolated perfused rabbit proximal convoluted tubules using a fluorescent indicator.
Authors:Krapf R, Berry CA, Verkman AS
Journal:Biophys J
PubMed ID:3395662
'The methodology has been developed to measure cell chloride activity by fluorescence microscopy using the chloride-sensitive dye, 6-methoxy-1-(3-sulfonatopropyl)quinolinium (SPQ). SPQ was loaded into cells of the in vitro microperfused rabbit proximal convoluted tubule by a 10 min luminal perfusion with 20 mM SPQ at 38 degrees C. Fluorescence was excited ... More
Regulation of Cl/HCO3 exchange in gastric parietal cells.
Authors:Thomas HA, Machen TE
Journal:Cell Regul
PubMed ID:1742343
'Microspectrofluorimetry of the fluorescent indicators 2&#39;,7&#39;-bis-(2-carboxyethyl)-5(and-6)carboxyfluorescein and 6-methoxy-N-(3-sulfopropyl)-quinolinium was used to measure intracellular pH (pHi), intracellular Cl (Cli), and transmembrane fluxes of HCO3 and Cl in single parietal cells (PC) in isolated rabbit gastric glands incubated in HCO3/CO2-buffered solutions. Steady-state pHi was 7.2 in both resting (50 microM cimetidine) and ... More