A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease. For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
사양
콘주게이트
Tb (Terbium)/Lanthanide Chelates
수량
25 μg
여기/방출
340⁄490, 520
반응성
Human
배송 조건
Dry Ice
판독
End Point
반응성 약어
Hu
타겟 유전자
Ser/Thr Kinases
제품라인
LanthaScreen™
구성 및 보관
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C.