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인용 및 참조 문헌 (319)
Invitrogen™
FM™ 4-64 Dye (N-(3-Triethylammoniumpropyl)-4-(6-(4-(Diethylamino) Phenyl) Hexatrienyl) Pyridinium Dibromide)
Styryl dye FM 4-64는 yeast 액포막(vacuolar membrane)을 적색 형광(최대 여기/방출 ∼515/640 nm)으로 선택적으로 염색한다고 보고되어 있습니다. 이 lipophilic dye는 공포성자세히 알아보기
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보기 방식 변경
| 카탈로그 번호 | 수량 |
|---|---|
| T13320 | 10 x 100μg |
| T3166 | 1mg |
카탈로그 번호 T13320
제품 가격(KRW)
810,000
Online offer
Ends: 31-Dec-2025
900,000할인액 90,000 (10%)
10 x 100 µg
수량:
10 x 100μg
제품 가격(KRW)
810,000
Online offer
Ends: 31-Dec-2025
900,000할인액 90,000 (10%)
10 x 100 µg
Styryl dye FM 4-64는 yeast 액포막(vacuolar membrane)을 적색 형광(최대 여기/방출 ∼515/640 nm)으로 선택적으로 염색한다고 보고되어 있습니다. 이 lipophilic dye는 공포성 소기관(vacuolar organelle)의 형태와 역학을 가시화하고 식균작용 경로 연구, yeast 세포내 섭취 돌연변이 탐색 및 분석에 중요한 도구입니다. FM 4-64는 1 mg 단일 vial (T-3166)로도 구입할 수 있습니다.
For Research Use Only. Not for use in diagnostic procedures.
사양
색상Red
검출 방법Fluorescence
용도(장비)Fluorescence Microscope
제품라인FM
수량10 x 100μg
배송 조건Room Temperature
라벨 유형Fluorescent Dye
제품 유형Dye
SubCellular LocalizationPlasma Membrane
Unit Size10 x 100 µg
구성 및 보관
Store at room temperature and protect from light.
자주 묻는 질문(FAQ)
I want to study endosomes trafficking using FM 4-64. Will the label be retained after fixation? And can I label already-fixed cells?
인용 및 참조 문헌 (319)
인용 및 참조 문헌
Abstract
Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways.
Journal:The Journal of cell biology
PubMed ID:10662773
In nutrient-rich, vegetative conditions, the yeast Saccharomyces cerevisiae transports a resident protease, aminopeptidase I (API), to the vacuole by the cytoplasm to vacuole targeting (Cvt) pathway, thus contributing to the degradative capacity of this organelle. When cells subsequently encounter starvation conditions, the machinery that recruited precursor API (prAPI) also sequesters
Glutamate induces the rapid formation of spine head protrusions in hippocampal slice cultures.
Journal:Proceedings of the National Academy of Sciences of the United States of America
PubMed ID:15831587
Synaptic plasticity at neuronal connections has been well characterized functionally by using electrophysiological approaches, but the structural basis for this phenomenon remains controversial. We have studied the dynamic interactions between presynaptic and postsynaptic structures labeled with FM 4-64 and a membrane-targeted GFP, respectively, in hippocampal slices. Under conditions of reduced
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis.
Journal:The Journal of cell biology
PubMed ID:9763421
The Saccharomyces cerevisiae FAB1 gene encodes a 257-kD protein that contains a cysteine-rich RING-FYVE domain at its NH2-terminus and a kinase domain at its COOH terminus. Based on its sequence, Fab1p was initially proposed to function as a phosphatidylinositol 4-phosphate (PtdIns(4)P) 5-kinase (). Additional sequence analysis of the Fab1p kinase
Slow spontaneous secretion from single large dense-core vesicles monitored in neuroendocrine cells.
Journal:FASEB J
PubMed ID:15180959
Hormones are released from cells by passing through an exocytotic pore that forms after vesicle and plasma membrane fusion. In stimulated exocytosis vesicle content is discharged swiftly. Although rapid vesicle discharge has also been proposed to mediate basal secretion, this has not been studied directly. We investigated basal hormone release
Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator.
Journal:J Cell Biol
PubMed ID:12538638
'Newly synthesized proteins that do not fold correctly in the ER are targeted for ER-associated protein degradation (ERAD) through distinct sorting mechanisms; soluble ERAD substrates require ER-Golgi transport and retrieval for degradation, whereas transmembrane ERAD substrates are retained in the ER. Retained transmembrane proteins are often sequestered into specialized ER