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Citations & References (1)
Invitrogen™
BLOCK-iT™ Transfection Kit
The BLOCK-iT™ Transfection Kit contains everything you need for successful high-efficiency transfection of siRNA into cells. Each kit contains Lipofectamine™Read more
| Catalog Number | Quantity |
|---|---|
| 13750070 | 1 Kit |
Catalog number 13750070
Price (MXN)
-
Quantity:
1 Kit
The BLOCK-iT™ Transfection Kit contains everything you need for successful high-efficiency transfection of siRNA into cells. Each kit contains Lipofectamine™ 2000 Transfection Reagent for efficient delivery in a broad range of cell lines and the BLOCK-iT™ Fluorescent Oligo for use as an indicator of transfection efficiency. The BLOCK-iT™ Fluorescent Oligo provides:
–A strong, easily detectable fluorescein signal indicating transfection efficiency
–Chemical modifications for a clearer, more persistent cellular signal than labeled siRNA
–Proven correlation of transfection efficiency with Stealth RNAi™ siRNA and traditional siRNA molecules
–A strong, easily detectable fluorescein signal indicating transfection efficiency
–Chemical modifications for a clearer, more persistent cellular signal than labeled siRNA
–Proven correlation of transfection efficiency with Stealth RNAi™ siRNA and traditional siRNA molecules
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Control TypeTransfection Control
For Use With (Application)Transfection
Product LineBLOCK-iT
Product TypeTransfection Kit
Quantity1 Kit
Reagent TypeRNA
FormatKit
Sample TypeSynthetic siRNA
Transfection TechniqueLipid-based Transfection
Unit SizeEach
Contents & Storage
Each kit contains 125 μl of 20 μM BLOCK-iT™ Fluorescent Oligo and 250 μl of Lipofectamine™ 2000 Reagent. Store the BLOCK-iT™ Fluorescent Oligo at -20°C and Lipofectamine™ 2000 at +4°C
Citations & References (1)
Citations & References
Abstract
CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
Journal:Proc Natl Acad Sci U S A
PubMed ID:15890777
'gamma-Secretase is a membrane protein complex that cleaves the beta-amyloid precursor protein (APP) within the transmembrane region, after prior processing by beta-secretase, producing amyloid beta-peptides Abeta(40) and Abeta(42). Errant production of Abeta-peptides that substantially increases Abeta(42) production has been associated with the formation of amyloid plaques in Alzheimer''s disease patients.