5-ROX (5-Carboxy-X-Rhodamine, Triethylammonium Salt), single isomer
Citations & References (23)
Invitrogen™
5-ROX (5-Carboxy-X-Rhodamine, Triethylammonium Salt), single isomer
The carboxylic acid of 5-ROX is used for oligonucleotide labeling and automated DNA sequencing applications. Conjugates of this dye haveRead more
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Catalog Number
Quantity
C6124
10 mg
Catalog number C6124
Price (MXN)
-
Quantity:
10 mg
The carboxylic acid of 5-ROX is used for oligonucleotide labeling and automated DNA sequencing applications. Conjugates of this dye have longer-wavelength spectra than the spectra of Lisaamine™ rhodamine B conjugates, but somewhat shorter-wavelength spectra than those of Texas Red™ conjugates.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
Label or DyeROX
Product Type5-ROX
Quantity10 mg
Reactive MoietyCarboxylic Acid
Shipping ConditionRoom Temperature
Label TypeClassic Dyes
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Frequently asked questions (FAQs)
What is the excitation and emission wavelength for rhodamine?
Rhodamine is a generic term for a wide variety of cationic dyes whose fluorescence emission can range from green, orange to red. The table below lists the excitation and emission maxima (nm), as well as molar extinction coefficients (EC; cm-1 M-1), for various rhodamine dyes (data derived with dye dissolved in methanol).
Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.
Authors:van Triest B, Pinedo HM, Telleman F, van der Wilt CL, Jansen G, Peters GJ
Journal:Biochem Pharmacol
PubMed ID:9256160
'Resistance to some (lipophilic) antifolates has been associated with P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). A possible relationship with non-P-gp MDR has not been established. We studied resistance to antifolates in SW-1573 human lung carcinoma cells, a P-gp overexpressing variant SW-1573/2R160 and a multidrug resistance protein (MRP) overexpressing variant SW-1573/2R120. In ... More
Down-regulation of topoisomerase II by camptothecin does not prevent additive activity of the topoisomerase II inhibitor etoposide in vitro.
Authors:Stahl M, Kasimir-Bauer S, Harstrick A
Journal:Anticancer Drugs
PubMed ID:9311443
'Topoisomerases (Topo) I and II are cellular enzymes that catalyze the relaxation of topologically strained DNA and that are involved in a number of DNA-related processes. Their complete inhibition by Topo I and II inhibitors gives promise for improvements in the treatment of malignant diseases. However, preclinical studies showed down-regulation ... More
Evidence for uptake of vital dye by activated rat peritoneal mast cells: an in vitro imaging study.
Authors:Wei JY, Go VL, Taché Y, Kruger L
Journal:Neuroimage
PubMed ID:9343581
'Uptake of material from surrounding medium by activated rat peritoneal mast cells (PMCs) was studied using in vitro peritoneal eluate cells, the vital fluorescent dye sulforhodamine B (SFRM-B), secretagogue compound 48/80, and an imaging technique. PMCs, which undergo different states of degranulation, are shown to possess the ability to take ... More
Growth inhibition of human glioma cells induced by 8-chloroadenosine, an active metabolite of 8-chloro cyclic adenosine 3':5'-monophosphate.
Authors:Langeveld CH, Jongenelen CA, Heimans JJ, Stoof JC
Journal:Cancer Res
PubMed ID:1617676
'8-Chloroadenosine 3'':5''-monophosphate (8ClcAMP) inhibits the growth of human glioma cell lines at much lower concentrations than more commonly used cyclic AMP analogues, without inducing morphological differentiation. The mechanism by which 8ClcAMP exerts this effect is not fully understood. We examined whether the growth-inhibitory effect of this compound is due to ... More
Localization, physiology, and modulation of a molluskan dopaminergic synapse.
Authors:Magoski NS, Bulloch AG
Journal:J Neurobiol
PubMed ID:9298763
'We investigated the location, physiology, and modulation of an identified synapse from the central nervous system (CNS) of the mollusk Lymnaea stagnalis. Specifically, the excitatory synapse from interneuron right pedal dorsal one (RPeD1) to neurons visceral dorsal two and three (VD2/3) was examined. The gross and fine morphology of these ... More