QSY™ 9 C5-Maleimide
QSY&trade; 9 C<sub>5</sub>-Maleimide
Citations & References (2)
Invitrogen™

QSY™ 9 C5-Maleimide

The thiol-reactive quencher, QSY™ 9 C5-maleimide has a broad and intense visible absorption (∼560 nm) but no fluorescence making itRead more
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Catalog NumberQuantity
Q30457
also known as Q-30457
5 mg
Catalog number Q30457
also known as Q-30457
Price (MXN)
-
Quantity:
5 mg
The thiol-reactive quencher, QSY™ 9 C5-maleimide has a broad and intense visible absorption (∼560 nm) but no fluorescence making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityThiol
Label or DyeQSY™ 9
Product TypeMaleimide
Quantity5 mg
Reactive MoietyMaleimide
Shipping ConditionRoom Temperature
Label TypeQuencher Dyes
Product LineQSY
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.

Citations & References (2)

Citations & References
Abstract
High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
Authors:Shieh HS, Mathis KJ, Williams JM, Hills RL, Wiese JF, Benson TE, Kiefer JR, Marino MH, Carroll JN, Leone JW, Malfait AM, Arner EC, Tortorella MD, Tomasselli A,
Journal:J Biol Chem
PubMed ID:17991750
Aggrecanase-2 (a disintegrin and metalloproteinase with thrombospondin motifs-5 (ADAMTS-5)), a member of the ADAMTS protein family, is critically involved in arthritic diseases because of its direct role in cleaving the cartilage component aggrecan. The catalytic domain of aggrecanase-2 has been refolded, purified, and crystallized, and its three-dimensional structure determined to ... More
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
Authors:Hills R, Mazzarella R, Fok K, Liu M, Nemirovskiy O, Leone J, Zack MD, Arner EC, Viswanathan M, Abujoub A, Muruganandam A, Sexton DJ, Bassill GJ, Sato AK, Malfait AM, Tortorella MD
Journal:J Biol Chem
PubMed ID:17311924
ADAMTS-4 and ADAMTS-5 are aggrecanases responsible for the breakdown of cartilage aggrecan in osteoarthritis. Multiple ADAMTS-4 cleavage sites have been described in several matrix proteins including aggrecan, versican, and brevican, but no concise predictive cleavage motif has been identified for this protease. By screening a 13-mer peptide library with a ... More