ABI PRISM™ 7900HT Sequence Detection System User's Manual

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4317596	1 manual

Número de catálogo 4317596

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1 manual

This is the User's Manual for the ABI PRISM™ 7900HT Sequence Detection System.

For Research Use Only. Not for use in diagnostics procedures.

Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.

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Preguntas frecuentes

What type of Real-Time PCR (Sequence Detection System) information is available from Applied Biosystems?

Tutorials demonstrating introductions to Real-Time PCR, guidelines for designing real-time assays using Primer Express software, and various instrument set-ups can be found under Life Technologies University on our website. User bulletins, manuals and Product inserts, protocols can be found as downloadable pdf files on our Technical Resources page.

Find additional tips, troubleshooting help, and resources within our Real-Time PCR and Digital PCR Applications Support Center.

Citations & References (4396)

Citations & References

Abstract

Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats.

Authors:Wong H; Lehman-McKeeman LD; Grubb MF; Grossman SJ; Bhaskaran VM; Solon EG; Shen HS; Gerson RJ; Car BD; Zhao B; Gemzik B

Journal:Toxicological Sciences : An Official Journal of the Society of Toxicology

PubMed ID:

4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine (DMP 904) is a potent and selective antagonist of corticotropin releasing factor receptor-1 (CRF1 receptor) with an efficacious anxiolytic profile in preclinical animal models. In subchronic toxicity studies in Sprague-Dawley rats, DMP 904 produced thyroid follicular cell hypertrophy and hyperplasia, and a low incidence of follicular cell adenoma. The ... More

RAGE ligand upregulation of VEGF secretion in ARPE-19 cells.

Authors:Ma W; Lee SE; Guo J; Qu W; Hudson BI; Schmidt AM; Barile GR

Journal:Investigative Ophthalmology & Visual Science

PubMed ID:

PURPOSE: The importance of VEGF in stimulating neovascular age-related macular degeneration (AMD) is well-recognized, but the initiating factors that induce local upregulation of VEGF remain unclear. The current study was conducted to test the hypothesis that activation of RAGE (receptor for advanced glycation end products [AGEs]) by its ligands, including ... More

SEROTONIN POLYMORPHISMS AND POSTTRAUMATIC STRESS DISORDER IN A TRAUMA EXPOSED AFRICAN AMERICAN POPULATION

Authors:Mellman, TA; Alim, T; Brown, DD; Gorodetsky, E; Buzas, B; Lawson, WB; Goldman, D; Charney, DS

Journal:DEPRESSION AND ANXIETY

PubMed ID:

Background: Genetic polymorphisms that influence serotonin (5-hydroxytryptamine, 5HT) neurotransmission are candidates for contributing to susceptibility to posttraumatic stress disorder (PTSD). The objective of our study was to determine if a variable length polymorphism for the promoter regions of the 5HT transporter (5HTTLPR), and/or a substitution polymorphism. in the promoter region ... More

Cognitive Flexibility is Associated with KIBRA Variant and Modulated by Recent Tobacco Use

Authors:Zhang, HP; Kranzler, HR; Poling, J; Gruen, JR; Gelernter, J

Journal:NEUROPSYCHOPHARMACOLOGY

PubMed ID:

The kidney and brain expressed protein gene (KIBRA) and the calsyntenin 2 gene (CLSTN2) are reportedly involved in synaptic plasticity. Single nucleotide polymorphisms (SNPs) rs17070145 (KIBRA) and rs6439886 (CLSTN2) have been found to affect memory performance measures. This study examined the association of KIBRA SNP rs17070145 and CLSTN2 SNPs rs6439886 ... More

Phenomic determinants of genomic variation in autism spectrum disorders

Authors:Qiao, Y; Riendeau, N; Koochek, M; Liu, X; Harvard, C; Hildebrand, MJ; Holden, JJA; Rajcan-Separovic, E; Lewis, MES

Journal:Journal of Medical Genetics

PubMed ID:

Background: Autism spectrum disorders (ASDs) are common, heritable neurobiologic conditions of unknown aetiology confounded by significant clinical and genetic heterogeneity. Methods: This study evaluated a broad categorisation of phenotypic traits (or phenome) for 100 subjects with Autism Diagnostic Interview-Revised/Autism Diagnostic Observation Schedule-Generic (ADI-R/ADOS-G) confirmed idiopathic ASD undergoing 1 Mb ... More

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