KingFisher™ mL Purification System

Citas y referencias (6)

Thermo Scientific™

KingFisher™ mL Purification System

Automatice la preparación de muestras de bajo rendimiento en el flujo de trabajo del laboratorio con el sistema de purificación Thermo Scientific™ KingFisher mL

Número de catálogo	Cantidad
5400050	Cada uno

Número de catálogo 5400050

Precio (MXN)

Cantidad:

Cada uno

El sistema de purificación KingFisher™ ml está pendiente de suspensión. Thermo Fisher Scientific ofrece otras plataformas de automatización como el sistema de purificación Thermo Scientific™ KingFisher™ Duo Prime, el sistema de purificación KingFisher™ Flex y KingFisher Apex. La compañía continuará apoyando a los usuarios actuales de KingFisher™ mL con plásticos, servicio y soporte técnico a través del 2028, o todo lo posible.

Para el 1 de abril de 2023, Thermo Fisher Scientific pasará a una etapa de soporte limitada. Ofrecerá contratos de asistencia limitados y proporcionará los mejores servicios y asistencia posibles, sujetos a disponibilidad de piezas de repuesto y recursos.

Si está interesado en actualizar a uno de sus instrumentos de preparación de muestras más recientes, póngase en contacto con su administrador de cuentas local para obtener información sobre el producto. También puede visitar el siguiente sitio web para obtener más información: Modelos de sistemas de purificación de muestras KingFisher.

Características:

Purificación rápida y reproducible de ADN, ARN, proteínas y células de alta calidad para varios tipos de aplicaciones posteriores.
Sistema abierto y flexible que permite al cliente utilizar cualquier kit basado en partículas magnéticas para satisfacer las necesidades de cada aplicación
El software Thermo Scientific™ BindIt™ es fácil de usar y permite controlar el instrumento además de crear y modificar protocolos
Protocolos preconfigurados para distintos tipos de aplicaciones

Recomendada para:

Genómica y proteómica, descubrimiento de fármacos, descubrimiento de biomarcadores, control de calidad y ensayos de veterinaria

Para uso exclusivo en investigación.No apto para uso en procedimientos diagnósticos.

Especificaciones

Collection Efficiency of Particles95%

Fondo (imperial)11,4 in

Fondo (métrico)29 cm

DescripciónSistema de purificación KingFisher mL, 100-240 V, 50/60 Hz nominal

PantallaINICIAR/PARAR/DOS TECLAS DE CURSOR/LCD

Requisitos eléctricos100-240 V, 50/60 Hz

Para utilizar con (aplicación)Genómica y proteómica; descubrimiento de fármacos; descubrimiento de biomarcadores; control de calidad y ensayos de veterinaria

Altura (imperial)12,2 in

Altura (métrico)31 cm

Varillas magnéticasFormato de 3 x 5

Tamaño de partículas (métrico)aprox. > 1 μm

CantidadCada uno

Peine de puntasDiseño especial, formato de 1 x 5

Tipo de recipienteTira de tubos especial, 1 x 5 tubos

Peso (imperial)23 lb

Peso (métrico)10kg

Anchura (imperial)11,4 in

Anchura (métrico)29 cm

Capacidad15 muestras/ciclo

Volumen de procesamiento (métrico)De 50 to 1000 μL

Unit SizeEach

Preguntas frecuentes

Do you have scripts for using the MagMAX kits on the KingFisher mL instrument?

We do not have prewritten scripts for using MagMAX kits on the KingFisher mL instrument. We recommend adapting scripts written for the KingFisher Flex or KingFisher Presto instruments. You will still need to validate the scripts on your KingFisher mL instrument.

Find additional tips, troubleshooting help, and resources within our Automated Nucleic Acid Purification Support Center.

Can I use the MagMAX Express-96 Deep Well Head (Cat. No. 4388435) on the KingFisher 96 instrument?

Yes, the MagMAX Express-96 Deep Well Head can be used on the KingFisher 96 instrument. However, it is not compatible with the KingFisher Flex instrument.

Find additional tips, troubleshooting help, and resources within our Automated Nucleic Acid Purification Support Center.

What should I do if the tip comb does not load correctly onto my Thermo Scientific KingFisher system?

If the tip does not load correctly onto a Thermo Scientific KingFisher magnetic head, we recommend that you try manually flexing the tips both lengthwise and widthwise to level the tip comb. A video of flexing the tip comb can be found here: https://www.thermofisher.com/us/en/home/life-science/dna-rna-purification-analysis/automated-purification-extraction/kingfisher-systems/resources.html. The video is under "KingFisher Flex" and titled "How to install the magnet head and check the tip comb." Flexing of the tip comb is demonstrated at timepoint 1:35. If that does not work, try a different box or lot of tips. This applies to all KingFisher instruments.

Citations & References (6)

Citations & References

Abstract

Characterization of human cytochrome P450s involved in the bioactivation of tri-ortho-cresyl phosphate (ToCP).

Authors:Reinen J, Nematollahi L, Fidder A, Vermeulen NP, Noort D, Commandeur JN

Journal:

PubMed ID:25706813

'Tri-ortho-cresyl phosphate (ToCP) is a multipurpose organophosphorus compound that is neurotoxic and suspected to be involved in aerotoxic syndrome in humans. It has been reported that not ToCP itself but a metabolite of ToCP, namely, 2-(ortho-cresyl)-4H-1,2,3-benzodioxaphosphoran-2-one (CBDP), may be responsible for this effect as it can irreversibly bind to human ... More

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls.

Authors:Kvartsberg H, Portelius E, Andreasson U, Brinkmalm G, Hellwig K, Lelental N, Kornhuber J, Hansson O, Minthon L, Spitzer P, Maler JM, Zetterberg H, Blennow K, Lewczuk P

Journal:

PubMed ID:26136856

'Synaptic dysfunction and degeneration are central events in Alzheimer''s disease (AD) pathophysiology that are thought to occur early in disease progression. Synaptic pathology may be studied by examining protein biomarkers specific for different synaptic elements. We recently showed that the dendritic protein neurogranin (Ng), including the endogenous Ng peptide 48 ... More

Brain amyloid-beta fragment signatures in pathological ageing and Alzheimer's disease by hybrid immunoprecipitation mass spectrometry.

Authors:Portelius E, Lashley T, Westerlund A, Persson R, Fox NC, Blennow K, Revesz T, Zetterberg H

Journal:

PubMed ID:25591542

'Senile plaques in Alzheimer''s disease (AD) are composed of amyloid-ß (Aß), especially N-truncated forms including Aß4-42. These are thought to be neurotoxic. However, individuals may live for decades with biomarker evidence of cerebral ß-amyloidosis (positive amyloid PET imaging and/or low cerebrospinal fluid levels of the 42 amino acid form of ... More

APP metabolism regulates tau proteostasis in human cerebral cortex neurons.

Authors:Moore S, Evans LD, Andersson T, Portelius E, Smith J, Dias TB, Saurat N, McGlade A, Kirwan P, Blennow K, Hardy J, Zetterberg H, Livesey FJ

Journal:

PubMed ID:25921538

'Accumulation of Aß peptide fragments of the APP protein and neurofibrillary tangles of the microtubule-associated protein tau are the cellular hallmarks of Alzheimer''s disease (AD). To investigate the relationship between APP metabolism and tau protein levels and phosphorylation, we studied human-stem-cell-derived forebrain neurons with genetic forms of AD, all of ... More

Highly potent soluble amyloid-ß seeds in human Alzheimer brain but not cerebrospinal fluid.

Authors:Fritschi SK, Langer F, Kaeser SA, Maia LF, Portelius E, Pinotsi D, Kaminski CF, Winkler DT, Maetzler W, Keyvani K, Spitzer P, Wiltfang J, Kaminski Schierle GS, Zetterberg H, Staufenbiel M, Jucker M

Journal:

PubMed ID:25212850

The soluble fraction of brain samples from patients with Alzheimer's disease contains highly biologically active amyloid-ß seeds. In this study, we sought to assess the potency of soluble amyloid-ß seeds derived from the brain and cerebrospinal fluid. Soluble Alzheimer's disease brain extracts were serially diluted and then injected into the ... More

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