GeneChip™ miRNA 4.1 Array Plate
Applied Biosystems™

GeneChip™ miRNA 4.1 Array Plate

Many diseases, including cancer, are frequently described as diseases of disordered gene expression. It is estimated that more than 30%Más información
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Número de catálogoNúmero de arrays
902408TS16 matrices
90240924 matrices
90241096 matrices
Número de catálogo 902408TS
Precio (MXN)
-
Número de arrays:
16 matrices
Many diseases, including cancer, are frequently described as diseases of disordered gene expression. It is estimated that more than 30% of protein translation of coding genes is regulated by miRNA. There is also a large amount of growing evidence suggesting miRNA interacts with long non-coding RNA in the signaling networks that regulate alternative splicing events, which impacts cellular processes such as apoptosis, proliferation, and differentiation. All of which have shown to be causative elements in diseases such as cancer.

Measuring the changes in these critical nodes of regulation is extremely important for deciphering the biological context of differentially expressed genes. This array design is a powerful tool for studying the role of small non-coding RNAs and their involvement in a broad spectrum of developmental and physiological mechanisms.

To keep pace with the discovery of new and novel miRNA, we are pleased to offer the miRNA 4.1 96-Array Plates and Trays in our catalog of miRNA arrays. This product offers updated content with the same high performance as the previous generation array.

miRNA 4.1 Array Plates and Trays help bring you closer to biology with:
Comprehensive coverage – Designed to interrogate all mature miRNA sequences in miRBase Release 20
Easily correlate miRNA results – Analysis files contain host gene ID, predicted and validated miRNA target genes, and clustered miRNA information
Easy analysis – Analyze human, mouse, rat, or every miRNA for all species using the same array
Low sample input – Requires as little as 130 ng total RNA
Simple, fast, and free analysis solution – Coupled with Expression Console™ Software and Transcriptome Analysis Console (TAC) Software, researchers have a complete solution from data to decision-making in minutes

Related Links
GeneTitan™ Wash Buffers A and B Module
B2 Control Oligo (3nM)
Genetitan™ miRNA Array Holding Buffer
FlashTag™ Biotin HSR RNA Labeling Kits
FlashTag™ Biotin HSR RNA Labeling Kits
GeneTitan™ Hybridization Module for miRNA Plates
GeneChip™ Hybridization Control Kit
For Research Use Only. Not for use in diagnostic procedures.
Especificaciones
Cantidad1 x 16-array plate
TipomiRNA 4.1 Array Plate
matriz, red, conjuntomiRNA Profiling
FormatoArray Plate
Número de arrays16 matrices
EspecieAll Organisms
Unit SizeEach

Preguntas frecuentes

Is the hybridization mix for cartridges the same as the hybridization mix for PEG arrays (array plates)?

The hybridization mix for PEG arrays is different from the hybridization mix for cartridges. The concentrations of the hybridization mix are different and in addition, DMSO is not added into the hybridization mix for PEG arrays because it can affect the glue that holds the PEG to the plate.

Where can I find the species information for your GeneChip miRNA arrays?

The species information can be found in the annotation file of the miRNA array of interest.
Please complete the following steps:
- Go to www.thermofisher.com and go to the product page of the array of interest.
- Scroll down to support files.
- Download the annotation files for the miRNA array of interest, and open in excel.
- In the file, there will be a column, species scientific name. This column will have all the species present on the array.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

Does having multiple copies of the same probe across species impact hybridization in miRNA arrays?

Due to certain miRNAs being conserved across species, there may be multiple copies of the same probe across the miRNA arrays. However, sample processing with the FlashTag Biotin HSR RNA Labeling Kits ensures that there is excess target compared to the probes on the array. Consequently, there is enough sample available to hybridize onto all the replicate probes.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

Which assay do you recommend for use with Affymetrix miRNA Array Plates?

We only support use of the Affymetrix FlashTag Biotin HSR RNA Labeling Kit for preparing targets to be applied to GeneChip miRNA Array .

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.