Efficient-Pro™ AGT™ Medium (+) Insulin

Efficient-Pro AGT Medium (+) Insulin is a dry-format next-generation Chinese Hamster Ovary (CHO) medium used in the production of proteins such as monoclonal antibodies (mAbs), offering significant performance and ease-of-use improvements compared to other products.

Designed to work optimally with the Efficient-Pro Feed system, Efficient-Pro AGT Medium (+) Insulin has been formulated specifically for use with insulin-dependent CHO cell lines. The Efficient-Pro system increases titer and specific productivity, improves protein quality, and is easier to use and scale with convenient formats and multiple packaging configurations available.

Features of Efficient-Pro AGT Medium (+) Insulin include:

• Benefit from the ease-of-use associated with Gibco Advanced Granulation technology (AGT) for auto-pH and simplified dissolution
• Supports the growth and productivity of insulin-dependent CHO cell lines
• Sustains cell viability for longer bioreactor runs and maximized titer
• Helps speed up process development and streamline transfer to manufacturing scale
• Increases flexibility with a range of format and packaging configurations

Efficient-Pro AGT Medium (+) Insulin is a chemically defined and animal-origin-free (AOF) cell culture medium based on the Efficient-Pro AGT Medium formulation with the addition of recombinant human insulin. It is designed for the bioproduction of mAbs and other therapeutic proteins in both batch and fed-batch bioprocessing workflows. It helps support the growth and productivity of insulin-dependent CHO cell lines by eliminating the need for manual insulin supplementation. This modification reduces handling steps, minimizes variability, and improves workflow efficiency. Designed to be paired with the Efficient-Pro Feed system, Efficient-Pro AGT Medium (+) Insulin provides the power to help achieve high titers, specific productivity, and the simplicity to start process development faster, facilitate easier adaptation, and transfer to manufacturing scale with ease.