BODIPY™ 581/591 C11 (sensor de peroxidación de lípidos)
BODIPY™ 581/591 C11 (sensor de peroxidación de lípidos)
Citas y referencias (47)
Invitrogen™

BODIPY™ 581/591 C11 (sensor de peroxidación de lípidos)

El ácido undecanoico BODIPY™ 581/591 se puede utilizar para detectar especies reactivas de oxígeno (ROS) en células y membranas. LaMás información
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Número de catálogoCantidad
D38611 mg
Número de catálogo D3861
Precio (MXN)
-
Cantidad:
1 mg
El ácido undecanoico BODIPY™ 581/591 se puede utilizar para detectar especies reactivas de oxígeno (ROS) en células y membranas. La oxidación de la porción de butadienil poliinsaturada del colorante provoca un cambio de pico de emisión de fluorescencia de ∼ 590 nm a ∼ 510 nm.
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Cantidad1 mg
Método de detecciónFluorescencia
Excitation/Emission581/591 nm
IndicatorROS
Línea de productosBODIPY
Tipo de productoLipid Sensor
Unit SizeEach

Preguntas frecuentes

What solvent should be used to reconstitute/dissolve BODIPY 581/591 C11 (Lipid Peroxidation Sensor) (Cat. No. D3861)?

For BODIPY 581/591 C11 (Cat No. D3861), we recommend that you dissolve this in dimethyl sulfoxide (DMSO). You can prepare a stock solution in any concentration between 1 and 5 mg/mL. Please note that the BODIPY/DMSO stock solution must be stored at -20 degrees C, desiccated and protected from light.

Find additional tips, troubleshooting help, and resources within our Cell Imaging Support Center.

Citations & References (47)

Citations & References
Abstract
Cell death during ischemia: relationship to mitochondrial depolarization and ROS generation.
Authors:Levraut J, Iwase H, Shao ZH, Vanden Hoek TL, Schumacker PT
Journal:Am J Physiol Heart Circ Physiol
PubMed ID:12388276
Ischemia-reperfusion injury induces cell death, but the responsible mechanisms are not understood. This study examined mitochondrial depolarization and cell death during ischemia and reperfusion. Contracting cardiomyocytes were subjected to 60-min ischemia followed by 3-h reperfusion. Mitochondrial membrane potential (DeltaPsi(m)) was assessed with tetramethylrhodamine methyl ester. During ischemia, DeltaPsi(m) decreased to ... More
Improved efficacy of stem cell labeling for magnetic resonance imaging studies by the use of cationic liposomes.
Authors:van den Bos EJ, Wagner A, Mahrholdt H, Thompson RB, Morimoto Y, Sutton BS, Judd RM, Taylor DA
Journal:Cell Transplant
PubMed ID:14653621
'Labeling stem cells with FDA-approved superparamagnetic iron oxide particles makes it possible to track cells in vivo with magnetic resonance imaging (MRI), but high intracellular levels of iron can cause free radical formation and cytotoxicity. We hypothesized that the use of cationic liposomes would increase labeling efficiency without toxic effects. ... More
Action of DCFH and BODIPY as a probe for radical oxidation in hydrophilic and lipophilic domain.
Authors:Yoshida Y, Shimakawa S, Itoh N, Niki E
Journal:Free Radic Res
PubMed ID:14567446
'Fluorogenic probes such as 2'',7''-dichlorofluorescin (DCFH) have been extensively used to detect oxidative events and to measure antioxidant capacity. At the same time, however, the inherent drawbacks of these probes such as non-specificity towards oxidizing species have been pointed out. The present study was carried out to analyze the action ... More
A method to measure the oxidizability of both the aqueous and lipid compartments of plasma.
Authors:Aldini G, Yeum KJ, Russell RM, Krinsky NI
Journal:Free Radic Biol Med
PubMed ID:11677037
'The lipophilic radical initiator (MeO-AMVN) and the fluorescent probe C11BODIPY581/591 (BODIPY) were used to measure the lipid compartment oxidizability of human plasma. Aqueous plasma oxidizability was initiated by the aqueous peroxyl radical generator, AAPH, and 2'',7''-dichlorodihydrofluorescein (DCFH) was employed as the marker of the oxidative reaction. The distribution in aqueous ... More
Detection of lipid peroxidation in equine spermatozoa based upon the lipophilic fluorescent dye C1l-BODIPY581/591.
Authors:Ball BA, Vo A
Journal:J Androl
PubMed ID:11868820
'The lipophilic fluorescent probe, 4,4-difluoro-5-(4-phenyl-1 ,3-butadienyl)-4-bora-3a,4a-diaza-s-indacene-3-undecanoic acid (C11-BODIPY581/591) was used to evaluate changes in lipid peroxidation in equine spermatozoa during both short-term exposure to ferrous sulfate and sodium ascorbate in the presence of cumene hydroperoxide as well as during storage of spermatozoa at 5 degrees C for 48 hours. Peroxidation ... More
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