Mag-fura-2, AM es un indicador de magnesio intracelular de alta afinidad que es radiométrico y excitable mediante luz UV. EstaMás información
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Número de catálogo
Cantidad
M1292
20 x 50 μg
Número de catálogo M1292
Precio (MXN)
-
Cantidad:
20 x 50 μg
Mag-fura-2, AM es un indicador de magnesio intracelular de alta afinidad que es radiométrico y excitable mediante luz UV. Esta forma de acetoximetil (AM) éster es útil para la carga intracelular no invasiva y está disponible en paquetes de cantidades de 1 mg (M1291). También hay disponible una forma salina de tetrapotasio (M1290) con permeabilidad celular del colorante.
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Método de detecciónFluorescente
Tipo de coloranteA base de colorantes fluorescentes
Cantidad20 x 50 μg
Condiciones de envíoTemperatura ambiente
Para utilizar con (aplicación)Viabilidad y proliferación celulares
Para utilizar con (equipo)Microscopio de fluorescencia, Microfotómetro, Citómetro de flujo
Tipo de productoIndicador de magnesio
Unit SizeEach
Contenido y almacenamiento
Almacenar en el congelador de -5 °C a -30 °C y proteger de la luz.
Citations & References (259)
Citations & References
Abstract
Functional implications of calcium permeability of the channel formed by pannexin 1.
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap junction channels between adjacent cells, thus, allowing direct intercellular Ca(2+) diffusion and facilitating intercellular Ca(2+) wave propagation. More ... More
Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro.
Authors:Zhang J, Zhao F, Zhao Y, Wang J, Pei L, Sun N, Shi J,
Journal:J Biol Chem
PubMed ID:21487014
TRPM7, a divalent cation channel, plays an important role in neurons damaged from cerebral ischemia due to permitting intracellular calcium overload. This study aimed to explore whether magnesium was transported via a TRPM7 channel into the intracellular space of rat hippocampal neurons after 1 h of oxygen-glucose deprivation (OGD) and ... More
Effects of serum amyloid a and lysophosphatidylcholine on intracellular calcium concentration in human coronary artery smooth muscle cells.
Serum amyloid A (SAA), an acute-phase protein, and lysophosphatidylcholine (LPC), an oxidized LDL component, contribute to the physiological processes of atherosclerosis and cardiovascular disease. However, the effects of SAA/LPC on human coronary artery smooth muscle cells (hCASMCs) have not been fully investigated. Therefore, we examined the effects of SAA/LPC on ... More
Cellular mechanisms of vasopressin and endothelin to mobilize [Mg2+]i in vascular smooth muscle cells.
Authors:Okada K, Ishikawa S, Saito T
Journal:Am J Physiol
PubMed ID:1415672
The present study was undertaken to examine the effects of arginine vasopressin (AVP) and endothelin-1 (ET-1) on cytosolic free Mg2+ ([Mg2+]i) in cultured rat vascular smooth muscle cells (VSMC). [Mg2+]i was measured using the fluorescence indicator dye mag-fura-2. AVP and ET-1 at a concentration of 1 x 10(-9) M or ... More
Elevation of extracellular magnesium rapidly raises intracellular free Mg<sup>2+</sup> in human aortic endothelial cells: is extracellular Mg<sup>2+</sup> a regulatory cation?