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Citas y referencias (177)
Invitrogen™
Alpha-Bungarotoxin Conjugates
Thermo Fisher Scientific ofrece una amplia selección de conjugados de alfa-bungarotoxina de Invitrogen, incluidos conjugados Alexa Flour y Alexa Flour Plus.
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| Número de catálogo | Etiqueta o tinte |
|---|---|
| T1175 | Tetrametilrodamina |
| B56130 | Alexa Fluor™ Plus 405 |
| B13422 | Alexa Fluor™ 488 |
| B35451 | Alexa Fluor™ 555 |
| B13423 | Alexa Fluor™ 594 |
| B35450 | Alexa Fluor™ 647 |
| B1196 | Biotin-XX |
| B1601 | Sin marcar |
Número de catálogo T1175
Precio (MXN)
-
Etiqueta o tinte:
Tetrametilrodamina
Thermo Fisher Scientific ofrece una amplia selección de conjugados de alfa-bungarotoxina de Invitrogen, incluidos conjugados Alexa Flour y Alexa Flour Plus. El alfa-bungarotoxina, un aminoácido péptido de 74 aminoácidos extraído del veneno de Bungarus multicinctus, se une con alta afinidad a la subunidad A del receptor nicotínico de acetilcolina (AChR) de las uniones neuromusculares.
Thermo Fisher Scientific ofrece una amplia selección de conjugados de alfa-bungarotoxina de Invitrogen, incluidos conjugados Alexa Fluor y Alexa Fluor Plus. El alfa-bungarotoxina, un aminoácido péptido de 74 aminoácidos extraído del veneno de Bungarus multicinctus, se une con alta afinidad a la subunidad A del receptor nicotínico de acetilcolina (AChR) de las uniones neuromusculares. Nuestra brillante y fotoestable Alexa Fluor 555 alfa-bungarotoxina es una opción superior de sonda para visualizar este receptor.
Los conjugados fluorescentes de alfa-bungarotoxina se pueden utilizar para facilitar la identificación de AChRs nicotínicos y la localización de uniones neuromusculares. La alfa-bungarotoxina conjugada se ha utilizado en diversas aplicaciones, como la inmunofluorescencia (IF), la inmunohistoquímica (IHC) y la citometría de flujo (FC).
Los conjugados fluorescentes de alfa-bungarotoxina se pueden utilizar para facilitar la identificación de AChRs nicotínicos y la localización de uniones neuromusculares. La alfa-bungarotoxina conjugada se ha utilizado en diversas aplicaciones, como la inmunofluorescencia (IF), la inmunohistoquímica (IHC) y la citometría de flujo (FC).
For Research Use Only. Not for use in diagnostic procedures.
Especificaciones
ColorAmarillo
Método de detecciónFluorescencia
Para utilizar con (equipo)Microscopio de fluorescencia
Etiqueta o tinteTetrametilrodamina
Tipo de productoTetrametilrodamina α- bungarotoxina
Cantidad500 μg
Condiciones de envíoTemperatura ambiente
Localización subcelularReceptores
Excitation/Emission554/577 nm
Unit Size500 μg
Contenido y almacenamiento
Almacenar en el congelador (de –5 °C a –30 °C) y proteger de la luz.
Citations & References (177)
Citations & References
Abstract
Acetylcholine receptor aggregation at nerve-muscle contacts in mammalian cultures: induction by ventral spinal cord neurons is specific to axons.
Journal:J Neurosci
PubMed ID:7472493
We used a novel mammalian coculture system to study ACh receptor (AChR) redistribution and synaptic structure at nerve-muscle contacts. Ventral spinal cord (VSC) neurons were plated on cultures containing extensive myotubes but few fibroblasts. Neurite-induced redistribution of AChRs occurred within 6 hr after plating neurons and was maximal between 36-48
Signaling by insulin-like growth factors in paralyzed skeletal muscle: rapid induction of IGF1 expression in muscle fibers and prevention of interstitial cell proliferation by IGF-BP5 and IGF-BP4.
Journal:J Neurosci
PubMed ID:7514217
'In the absence of muscle activity, muscle fibers, muscle interstitial cells, and intramuscular nerves display characteristic reactions presumably aimed at restoring a functioning neuromuscular system and avoiding degenerative events. In partially denervated muscle these include proliferation of interstitial cells, followed by nerve sprouting. The same reactions can be induced in
Identification of nicotinic acetylcholine receptor recycling and its role in maintaining receptor density at the neuromuscular junction in vivo.
Journal:J Neurosci
PubMed ID:16251443
'In the CNS, receptor recycling is critical for synaptic plasticity; however, the recycling of receptors has never been observed at peripheral synapses. Using a novel imaging technique, we show here that nicotinic acetylcholine receptors (AChRs) recycle into the postsynaptic membrane of the neuromuscular junction. By sequentially labeling AChRs with biotin-bungarotoxin
The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane.
Journal:J Cell Biol
PubMed ID:11157973
'The dystrophin-associated protein (DAP) complex spans the sarcolemmal membrane linking the cytoskeleton to the basement membrane surrounding each myofiber. Defects in the DAP complex have been linked previously to a variety of muscular dystrophies. Other evidence points to a role for the DAP complex in formation of nerve-muscle synapses. We
Long-term maintenance of presynaptic function in the absence of target muscle fibers.
Journal:J Neurosci
PubMed ID:7666196
'Here we have investigated the role of the muscle fiber in the maintenance of presynaptic function at frog motor nerve terminals. Muscle fibers were selectively damaged and prevented from regenerating while leaving the motor innervation intact. Presynaptic activity of the resulting target-deprived nerve terminals was assayed using the fluorescent dye,