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Thermo Scientific Chemicals

3-(3,4-Dihydroxyphenyl)-L-alanine, 99%

Name: 3-(3,4-Dihydroxyphenyl)-L-alanine, 99%
SKU: 167530050

3-(3,4-Dihydroxyphenyl)-L-alanine (levodopa orL-dopa), CAS # 59-92-7, is a dopamine precursor molecule. | CAS: 59-92-7 | C9H11NO4 | 197.19 g/mol

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Catalog number 167530050

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5 g

Packaging:

Glass Bottle

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Chemical Identifiers

CAS59-92-7

IUPAC Name(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid

Molecular FormulaC9H11NO4

InChI KeyWTDRDQBEARUVNC-LURJTMIESA-N

SMILESN[C@@H](CC1=CC=C(O)C(O)=C1)C(O)=O

Specifications

Specification Sheet

Appearance (Form)Crystalline powder

HPLC>=98.5 %

Sulfated ash=<0.1 %

Titration with HClO4>=98.5 % (On dried substance)

Appearance (Color)White to cream

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 3-(3,4-Dihydroxyphenyl)-L-alanine, or L-dopa, is converted to dopamine by DOPA decarboxylase in the body

• Upon conversion to dopamine, it acts as an excitatory neurotransmitter

Applications

• L-dopa is useful in the laboratory study of Parkinson’s to replenish dopamine in depleted circuits

• L-dopa has also been used for laboratory research on hypertension and melanocyte activity

RUO – Research Use Only

General References:

Maini Rekdal, V.; Bess, E.N.; Bisanz, J.E.; Turnbaugh, P.J.; Balskus EP. Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism. Science. 2019, 364(6445), eaau6323.
Hong, C.T.; Chan, L.; Bai, C.H. The Effect of Caffeine on the Risk and Progression of Parkinson's Disease: A Meta-Analysis. Nutrients. 2020, 12(6), 1860.