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Citations & References (3)
Thermo Scientific™
MBS (m-maleimidobenzoyl-N-hydroxysuccinimide ester)
Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of aRead more
| Catalog Number | Quantity |
|---|---|
| 22311 | 50 mg |
Catalog number 22311
Price (TWD)
3,900.00
Precio exclusivo en nuestra web
Ends: 31-Dec-2025
5,560.00Save 1,660.00 (30%)
Each
Quantity:
50 mg
Price (TWD)
3,900.00
Precio exclusivo en nuestra web
Ends: 31-Dec-2025
5,560.00Save 1,660.00 (30%)
Each
Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
Features of MBS:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-MBS
• Popular for forming enzyme immunoconjugates
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-MBS (m-maleimidobenzoyl-N-hydroxysulfosuccinimide ester)
Features of MBS:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-MBS
• Popular for forming enzyme immunoconjugates
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-MBS (m-maleimidobenzoyl-N-hydroxysulfosuccinimide ester)
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Cell PermeabilityYes
DescriptionMBS
FormPowder
Labeling MethodChemical Labeling
Molecular Weight (g/mol)314.25
PEGylatedNo
Product LinePierce
Quantity50 mg
Reactive MoietyMaleimide, NHS Ester
Shipping ConditionAmbient
SolubilityDMF, DMSO
Spacer Arm Length7.3 Å
Water SolubleNo
Chemical ReactivityAmine-Sulfhydryl
CleavableNo
Crosslinker TypeHeterobifunctional
FormatStandard
Product TypeCrosslinker
SpacerShort (<10 Å)
Unit SizeEach
Contents & Storage
Upon receipt store desiccated at 4°C.
Frequently asked questions (FAQs)
Can you provide the shelf-life for MBS (m-maleimidobenzoyl-N-hydroxysuccinimide ester)?
Citations & References (3)
Citations & References
Abstract
Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms.
Journal:Nucleic Acids Res
PubMed ID:11024189
Different chemical methods used to attach oligonucleotides by their 5'-end on a glass surface were tested in the framework of solid phase PCR where surface-bound instead of freely-diffusing primers are used to amplify DNA. Each method was first evaluated for its capacity to provide a high surface coverage of oligonucleotides
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents.
Journal:J Biol Chem
PubMed ID:12972413
Heterobifunctional thiol to amine cross-linking agents were used to gain new insights on the dynamics and conformational factors governing the interaction between the cardiac Ca2+ pump (SERCA2a) and phospholamban (PLB). PLB is a small protein inhibitor of SERCA2a that reduces enzyme affinity for Ca2+ and thereby regulates cardiac contractility. We