Chloramphenicol, 98%

Name: Chloramphenicol, 98%
SKU: 227921000

Chloramphenicol, CAS # 56-75-7, is a preparation of the broad-spectrum, semisynthetic antibiotic.

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Catalog number 227921000

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Chemical Identifiers

CAS56-75-7

IUPAC Name2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Molecular FormulaC11H12Cl2N2O5

InChI KeyWIIZWVCIJKGZOK-UHFFFAOYNA-N

SMILESOCC(NC(=O)C(Cl)Cl)C(O)C1=CC=C(C=C1)[N+]([O-])=O

Specifications

Specification Sheet

Appearance (Color)White to yellowish-white to greyish-white

UV spectrophotometry98.0 to 102.0 % (on dried substance)

Specific optical rotation+18.5° to +20.5° (20°C, 589 nm) (c=6, ethanol)

Appearance (Form)Crystalline powder

Loss on drying=<0.5 % (105°C)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

Chloramphenicol is an organochloride compound that contains a nitrobenzene ring
Chloramphenicol acts as a bacteriostatic by binding the 50S ribosomal subunit and preventing peptide formation
Stops peptidyltransferase activity by complexing to 50S subunit

Applications

Intended for molecular and microbiology applications such as antibiotic resistance gene testing and selective growth experiments and as a selection agent in bacterial cell culture
For research use only

RUO – Research Use Only

Literature references: Polat, T. G.; Duman, O.; Tunç S. Agar/κ-carrageenan/montmorillonite nanocomposite hydrogels for wound dressing applications. Int J Biol Macromol. 2020, 164:4591-4602.