Vitamin D2, 97+%

Name: Vitamin D2, 97+%
SKU: 422630050

Vitamin D2, or Ergocalciferol, CAS # 50-14-6, a fat-soluble hormone that is important for calcium and phosphorus absorption and metabolism. | CAS: 50-14-6 | C28H44O | 396.66 g/mol

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1 g

5 g

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Glass bottle

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Catalog number 422630050

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Quantity:

5 g

Packaging:

Glass bottle

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Chemical Identifiers

CAS50-14-6

IUPAC Name(1S,3E)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol

Molecular FormulaC28H44O

InChI KeyMECHNRXZTMCUDQ-VLOQVYPSSA-N

SMILESCC(C)[C@@H](C)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)CCC1=C

Specifications

Specification Sheet

Infrared spectrumConforms

Appearance (Color)White to light yellow

Appearance (Form)Powder or crystals

Melting point113°C to 119°C

HPLC97.0 to 103.0 %

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Vitamin D2 (ergocalciferol) is a form of vitamin D, a fat-soluble hormone found in food sources
Vitamin D is important for calcium and phosphorus homeostasis, and can play a role in many biological processes including cell growth
Vitamin D2 has a lower binding affinity than Vitamin D3 for vitamin D binding protein

Applications

Research studies show that Vitamin D2 treatment in rats inhibits bladder tumor promotion
Studies show that the treatment of lung carcinoma cells with vitamin D2 in vitro resulted in increased ACE2 protein levels
Vitamin D2 has been seen to interfere with prion protein oligomerization in vitro

RUO – Research Use Only

General References:

Yazawa, Y., et al., 2000. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biological & pharmaceutical bulletin. 23(11): 1298-302.
Bártová, E.; Legartová, S.; Krejčí, J.; Arcidiacono, O.A. Cell differentiation and aging accompanied by depletion of the ACE2 protein. Aging (Albany NY). 2020, 12(22), 22495-22508.
Suenaga, M.; Hiramoto, Y.; Matsunaga, Y. Vitamin D 2 interacts with Human PrP(c) (90-231) and breaks PrP(c) oligomerization in vitro. Prion. 2013, 7(4), 312-8.
Soto-Dávila, M.; Valderrama, K.; Inkpen, S.M.; Hall, J.R.; Rise, M.L.; Santander, J. Effects of Vitamin D2 (Ergocalciferol) and D3 (Cholecalciferol) on Atlantic Salmon (Salmo salar) Primary Macrophage Immune Response to Aeromonas salmonicida subsp. salmonicida Infection. Front Immunol. 2020, 10, 3011.