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Thermo Scientific Chemicals
Cyclosporin A, 98%
Cyclosporin A, 98%, CAS # 59865-13-3, is a compound that shows immunosuppressive, antifungal, antirheumatic, and dermatologic activities. It is also a calcineurin and enzyme inhibitor. | CAS: 59865-13-3 | C62H111N11O12 | 1202.64 g/mol
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Chemical Identifiers
CAS59865-13-3
Specifications
Specification Sheet
Specification SheetAppearance (Color)White to almost white
Appearance (Form)Powder or crystalline powder
Infrared spectrumConforms
Loss on drying=<2.0 % (105°C, 3 hrs)
HPLC>=97.5 %
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum
RUO – Research Use Only
General References:
- Staudinger, L. A.; Spano, S. J.; Lee, W. S.; Coelho, N.; Moriarty, T. J.; McCulloch, C. A. Role of discoidin domain receptor 1 in dysregulation of collagen remodeling by cyclosporin A. Int. J. Biochem. Cell Biol. 2015, 62, 80-87.
- Petrillo, C.; Cesana, D.; Piras, F.; Bartolaccini, S.; Naldini, L.; Montini, E.; Rudnitski, A. K. Cyclosporin A and Rapamycin Relieve Distinct Lentiviral Restriction Blocks in Hematopoietic Stem and Progenitor Cells. Molecular Therapy 2015, 23 (2), 352-362.