This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Gabapentin is a water-soluble GABA analog with anticonvulsant and analgesic activities
• The exact mechanism of action is unknown but it has been described that this compound inhibits excitatory neuron activity by interacting with voltage-gated calcium channels in cortical neurons
Application
• Gabapentin has been used as the α2δ-ligand to examine whether the allyl isothiocyanate (AITC) sensitized thermal aversion assay might be useful as a screening method for the identification of presumptive analgesics