Cholic acid, 97%, Thermo Scientific Chemicals

Name: Cholic acid, 97%, Thermo Scientific Chemicals
SKU: A11257.36

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Catalog number A11257.36

also known as A11257-36

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Quantity:

500 g

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Chemical Identifiers

CAS81-25-4

IUPAC Name(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid

Molecular FormulaC24H40O5

InChI KeyBHQCQFFYRZLCQQ-OELDTZBJSA-N

SMILESC[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

Specifications

Specification Sheet

Melting Point (clear melt)197.0-204.0°C

Optical Rotation+33° to +38° (c=2.0 in methanol)

Appearance (Color)White to pale cream

FormCrystals or powder or crystalline powder

Assay (Aqueous acid-base Titration)≥96.0 to ≤103.0%

Cholic acid is used as a preservative for food. It is widely used as an intermediate in the manufacture of pharmaceuticals. It finds use in biological research. It helps in detergents to soften biological fats. It helps in preventing and melting gallstones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cholic acid is used as a preservative for food. It is widely used as an intermediate in the manufacture of pharmaceuticals. It finds use in biological research. It helps in detergents to soften biological fats. It helps in preventing and melting gallstones.

Solubility
Soluble in alcohols, acetone, dimethylsulfoxide, methanol. Insoluble in water.

Notes
Stable. Incompatible with other materials such as strong oxidizing agents.

RUO – Research Use Only

General References:

Huang, W.; Wang, X.; Shi, C.; Guo, D.; Xu, G.; Wang, L.; Bodman, A.; Luo, J. Fine-Tuning Vitamin E-Containing Telodendrimers for Efficient Delivery of Gambogic Acid in Colon Cancer Treatment. Mol. Pharmaceutics 2015, 12 (4), 1216-1229.
Jiang, W.; Luo, J.; Nangia, S. Multiscale Approach to Investigate Self-Assembly of Telodendrimer Based Nanocarriers for Anticancer Drug Delivery. Langmuir 2015, 31 (14), 4270-4280.