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Thermo Scientific Chemicals
Chloramine-T trihydrate, 98%
CAS: 7080-50-4 | C7H13ClNNaO5S | 281.68 g/mol
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Catalog number A12044.30
also known as A12044-30
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Quantity:
250 g
Chemical Identifiers
CAS7080-50-4
IUPAC Namesodium (chloroimino)(4-methylphenyl)-λ⁶-sulfanoylolate trihydrate
Molecular FormulaC7H13ClNNaO5S
InChI KeyRNROOTWAJBXJBD-UHFFFAOYSA-M
SMILESO.O.O.[Na+].CC1=CC=C(C=C1)S([O-])(=O)=NCl
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder
Assay (Iodometric Titration)≥97.5 to ≤102.5%
Identification (FTIR)Conforms
Appearance (Color)White
Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).
Solubility
Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.
Notes
Incompatible with strong oxidizing agents, acids and ammonia.
Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).
Solubility
Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.
Notes
Incompatible with strong oxidizing agents, acids and ammonia.
RUO – Research Use Only
General References:
- Mal, S.; Prathap, K. J.; Smith, S. C.; Umarye, J. D. Facile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T. Tetrahedron Lett. 2015, 56 (22), 2896-2901.
- Dzandzi, J. P. K.; Vera, D. R. B.; Genady, A. R.; Albu, S. A.; Eltringham-Smith, L. J.; Capretta, A.; Sheffield, W.P.; Valliant, J. F. Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis. J. Org. Chem. 2015, 80 (14), 7117-7125.