4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%

Name: 4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%
SKU: A12602.14

CAS: 345909-35-5 | C10H7NO3 | 189.17 g/mol

Change view

Quantity:

5 g

25 g

Try the chem dex^TM web app

Catalog number A12602.14

also known as A12602-14

Price (TWD)

Request A Quote

Quantity:

25 g

Request bulk or custom format

Chemical Identifiers

CAS345909-35-5

IUPAC Name4-hydroxyquinoline-2-carboxylic acid

Molecular FormulaC10H7NO3

InChI KeyHCZHHEIFKROPDY-UHFFFAOYSA-N

SMILESOC(=O)C1=NC2=CC=CC=C2C(O)=C1

Specifications

Specification Sheet

Appearance (Color)Dark cream to cream to yellow to green to pale brown to pale gray to gray

FormPowder

Assay (Silylated GC)≥97.5%

Identification (FTIR)Conforms

Water Content (Karl Fischer Titration)4.54-12.5% (0.5-1.5 waters)

Broad spectrum excitatory amino acid antagonist4-Hydroxyquinoline-2-carboxylic acid hydrate is used as an intermediate in synthetic chemistry. It acts as an antiexcitotoxic and anticonvulsant. It finds application in certain neurobiological disorders therapy.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in hot ethanol and water. Insoluble in ether.

Notes
Incompatible with oxidizing agents.

RUO – Research Use Only

General References:

Pesek, J.; Svoboda, J.; Sattler, M.; Bartram, S.; Boland, W. Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis. Org. Biomol. Chem. 2015, 13 (1), 178-184.
Tajti, J.; Majlath, Z.; Szok, D.; Csati, A.; Toldi, J.; Fulop, F.; Vecsei, L. Novel Kynurenic Acid Analogues in the Treatment of Migraine and Neurodegenerative Disorders: Preclinical Studies and Pharmaceutical Design. Curr. Pharm. Des. 2015, 21 (17), 2250-2258.