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Thermo Scientific Chemicals
beta-Cyclodextrin hydrate
CAS: 68168-23-0 | C42H70O35 | 1134.99 g/mol
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Specifications
Beilstein5915513
CAS68168-23-0
Chemical Name or Materialbeta-Cyclodextrin hydrate
EINECS Number231-493-2
Formula Weight1134.98 (Anhydrous)
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beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.
Solubility
Slightly soluble in water (18.5 g/L at 25°C).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.
Solubility
Slightly soluble in water (18.5 g/L at 25°C).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Thomas Steiner; Gertraud Koellner. Crystalline .beta.-Cyclodextrin hydrate at various humidities: Fast, continuous and reversible dehydration studied by X-ray diffraction. J. Am. Chem. Soc. 1994, 116, (12),5122-5128
- Christian Betzel; Wolfram Saenger; Brian E.Hingerty; George M.Brown. Topography of cyclodextrin inclusion complexes, part 20. Circular and flip-flop hydrogen bonding in .beta.-cyclodextrin undecahydrate: a neutron diffraction study. J. Am. Chem. Soc. 1984, 106, (24),7545-7557
- Has been used to influence regioselectivity in Diels-Alder reactions: J. Chem. Soc., Chem. Commun., 971 (1995); for reaction scheme, see 2,6-Dimethyl-p-benzoquinone, A11342. Encapsulation of aniline and N-substituted anilines allows regioselective bromination: Tetrahedron, 52, 3487 (1996). Catalyzes the Boc protection of amines with Di-tert-butyl dicarbonate, A14708 under neutral, aqueous conditions: Synlett, 1110 (2006).
- For a brief of uses as a supramolecular catayst in organic synthesis, see: Synlett, 175 (2007).