Sodium taurocholate hydrate, 96%
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Sodium taurocholate hydrate, 96%
Thermo Scientific Chemicals

Sodium taurocholate hydrate, 96%

Sodium taurocholate hydrate (CAS # 145-42-6) is a bile acid and detergent used in molecular biology for protein solubilization. | CAS: 345909-26-4 | C26H44NNaO7S | 537.688 g/mol
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Catalog number A18346.06
also known as A18346-06
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Chemical Identifiers
CAS345909-26-4
IUPAC Namesodium 2-[(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]ethane-1-sulfonate
Molecular FormulaC26H44NNaO7S
InChI KeyJAJWGJBVLPIOOH-IZYKLYLVSA-M
SMILES[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC(=O)NCCS([O-])(=O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Assay from Supplier's CofA≥95.0%
Water Content (Karl Fischer Titration)≤5.3%
Appearance (Color)White
Sodium taurocholate is a bile acid having detergent capabilities; natural surfactant. It is used for solubilization of protein. In the preparation of digestive enzymes, it is used as an emulsifier.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Sodium taurocholate hydrate is a bile acid conjugate of taurine and cholic acid that acts as a detergent
  • Sodium taurocholate solubilizes fats within the digestive system
  • It is the main component of bile acid in carnivorous animals; metabolites are also common in human bile

Application

  • Sodium taurocholate hydrate can be used as an emulsifier for protein isolation
RUO – Research Use Only

General References:

  1. Li, N.; Zhang, P.; Yang, C.; Zhu, Q.; Li, Z.; Li, F.; Han, Q.; Wang, Y.; Lv, Y.; Wei, P.; Liu, Z. Association of genetic variation of sodium taurocholatecotransporting polypeptide with chronic Hepatitis B Virus infection. Genet. Test. Mol. Biomarkers 2014, 18 (6), 425-429.
  2. Nagao, K.; Zhao, Y.; Takahashi,K.; Kimura,Y.; Ueda, K. Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation. J. Lipid Res. 2009, 50, 1165-1172.