Search
Element Search
Structure Search
Thermo Scientific Chemicals
4-Fluoro-3-nitrobenzotrifluoride, 97%
CAS: 367-86-2 | C7H3F4NO2 | 209.1 g/mol
Have Questions?
Change view
Catalog number A19676.22
also known as A19676-22
Price (TWD)
-
Quantity:
100 g
Chemical Identifiers
CAS367-86-2
IUPAC Name1-fluoro-2-nitro-4-(trifluoromethyl)benzene
Molecular FormulaC7H3F4NO2
InChI KeyHLDFCCHSOZWKAA-UHFFFAOYSA-N
SMILES[O-][N+](=O)C1=CC(=CC=C1F)C(F)(F)F
View more
Specifications
Specification Sheet
Specification SheetAssay (GC)≥96.0%
Refractive Index1.4595-1.4645 @ 20?C
Appearance (Color)Clear yellow to orange
FormLiquid
4-Fluoro-3-nitrobenzotrifluoride is used in the pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines. It may be used as derivatization reagent for the HPLC determination of polyamines. It was also used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids.
- [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids3
- 1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Fluoro-3-nitrobenzotrifluoride is used in the pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines. It may be used as derivatization reagent for the HPLC determination of polyamines. It was also used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids. • [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids3 • 1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one
Solubility
Insoluble in water.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
4-Fluoro-3-nitrobenzotrifluoride is used in the pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines. It may be used as derivatization reagent for the HPLC determination of polyamines. It was also used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids. • [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids3 • 1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one
Solubility
Insoluble in water.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Jorgen Vessman.; Signhild Stromberg. Determination of tranexamic acid in biological material by electron capture gas chromatography after direct derivatization in an aqueous medium. Anal. Chem. 1977, 49, (3), 369-373
- J. T. Gerig.; J. D. Reinheimer. Modification of human serum albumin with trifluoromethyl-substituted aryl halides and sulfonates J. Am. Chem. Soc. 1975, 97, (1), 168-173
- The nitro-group can be selectively displaced with KF in sulfolane, in the presence of phthaloyl chloride as a nitrite trap: J. Org. Chem., 56, 6406 (1991).