Tetracycline hydrochloride, 96%

Tetracycline hydrochloride, CAS # 64-75-5, is a wide-spectrum antibiotic that targets both gram-negative and gram-positive bacteria. | CAS: 64-75-5 | C22H25ClN2O8 | 480.898 g/mol

Catalog Number	Quantity
B21408.22 also known as B21408-22	100 g

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Catalog number B21408.22

also known as B21408-22

Price (TWD)

Quantity:

100 g

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Chemical Identifiers

CAS64-75-5

IUPAC Namehydrogen (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride

Molecular FormulaC22H25ClN2O8

InChI KeyDYQBMRZOOXYHIM-NCKOGSTASA-N

SMILES[H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O

Specifications

Loss on Drying≤ 2.0%

Appearance (Color)Yellow

FormCrystals or powder or crystalline powder

Assay from Supplier's CofA≥900 µg/mg (U.S. sourced material)

CommentMaterial Sourced in the U.S. and in other countries

Tetracycline hydrochloride is used to induce apoptosis in osteoclasts. It is used to treat acne and other skin infections, respiratory tract infections like pneumonia, genital, urinary infections, leptospirosis, helicobacter pylori, taxoplasmosis, mycoplasma, psittacosis for dog and cats. It also works more effectively in animals that have tick-borne infections. It is also useful in cell culture applications.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Tetracycline hydrochloride is the hydrochloride salt of the antibiotic tetracycline
Tetracycline blocks amino acyl-tRNA binding during bacterial protein synthesis
Tetracycline is a broad-spectrum naphthacene antibiotic that inhibits growth of both gram positive and gram negative bacteria

Applications

Tetracycline may be used as a selection agent in cell culture
It may also be used to activate inducible gene expression in engineered cells

RUO – Research Use Only

General References:

Chopra, I.; Roberts, M. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev. 2001, 65(2), 232-60.
Kenny, P.A.; Enver, T., Ashworth, A. Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line. BMC Mol Biol. 2002, 3:13.