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6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%, Thermo Scientific Chemicals
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6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%, Thermo Scientific Chemicals
6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%, Thermo Scientific Chemicals
6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride, 97%, Thermo Scientific Chemicals

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Catalog NumberQuantity
H33683.03
also known as H33683-03
1 g
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Catalog number H33683.03
also known as H33683-03
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Chemical Identifiers
CAS150020-64-7
IUPAC Name6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl chloride
Molecular FormulaC5H2Cl2N2O2S2
InChI KeyAPRATEMYDZDYJD-UHFFFAOYSA-N
SMILESClC1=C(N2C=CSC2=N1)S(Cl)(=O)=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White
FormCrystals or powder or crystalline powder
Melting Point (clear melt)136.5-142.5?C
Assay (Titration ex Chloride)≥96.0 to ≤104.0%
It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Solubility
Sparingly soluble in water.(0.26 g/L) (25°C),

Notes
Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. C. Elisabet Tranberg.; Andrea Zickgraf.; Brian N. Giunta.; Henning Luetjens.; Heidi Figler.; Lauren J. Murphree.; Ruediger Falke.; Holger Fleischer.; Joel Linden.; Peter J. Scammells.; Ray. A. Olsson. 2-Amino-3-aroyl-4,5-alkylthiophenes:  Agonist Allosteric Enhancers at Human A1 Adenosine Receptors.J. Med. Chem. 2002, 45 (2),382-389 .
  2. Robert H. Dodd.; Catherine Ouannes.; Malka Robert-Gero.; Pierre Potier. Hybrid molecules: growth inhibition of Leishmania donovani promastigotes by thiosemicarbazones of 3-carboxy-.beta.-carbolines.J. Med. Chem. 1989, 32 (6),1272-1276 .