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Thermo Scientific Chemicals
2-Ethoxyacetyl chloride, 97%, stab. with 0.3% Magnesium oxide
CAS: 14077-58-8 | C4H7ClO2 | 122.548 g/mol
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Catalog number H34443.22
also known as H34443-22
Price (TWD)
-
Quantity:
100 g
Chemical Identifiers
CAS14077-58-8
IUPAC Name2-ethoxyacetyl chloride
Molecular FormulaC4H7ClO2
InChI KeyZPMWWAIBJJFPPQ-UHFFFAOYSA-N
SMILESCCOCC(Cl)=O
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Specifications
Specification Sheet
Specification SheetRefractive Index1.4175-1.4225
Assay (GC)>96.0%
Formliquid
Appearance (Color)Clear, colourless to pale yellow
Assay (Titration ex Chloride)>96.0%
It is employed in fine chemical syntheses and used as pharmaceutical intermediates. A trace of cis-ethoxyacetamide was also detected and isolated with an authentic sample prepared from the reaction of cis-3-amino-6-methylchroman-4-01 (2) with 2-ethoxyacetyl chloride.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is employed in fine chemical syntheses and used as pharmaceutical intermediates. A trace of cis-ethoxyacetamide was also detected and isolated with an authentic sample prepared from the reaction of cis-3-amino-6-methylchroman-4-01 (2) with 2-ethoxyacetyl chloride.
Solubility
Insoluble in water.
Notes
Reacts with strong oxidizing agents. Store at room temperature.
It is employed in fine chemical syntheses and used as pharmaceutical intermediates. A trace of cis-ethoxyacetamide was also detected and isolated with an authentic sample prepared from the reaction of cis-3-amino-6-methylchroman-4-01 (2) with 2-ethoxyacetyl chloride.
Solubility
Insoluble in water.
Notes
Reacts with strong oxidizing agents. Store at room temperature.
RUO – Research Use Only
General References:
- Karen K. Bach.; Hesham R. El-Seedi.; Henrik M. Jensen.; Helene B. Nielsen.; Ib Thomsen.; Kurt B.G. Torssell. 1,3-Dipolar cycloadditions of ethoxycarbonyl-nitrile benzylimine, EtOOC C Full-size image (<1 K) - Full-size image (<1 K) CH2C6H5, and synthesis of β-amino acids. Synthesis and reactions of ethyl 2-chloro-2-ethoxyacetate and 2-chloro-2-ethoxyacetyl chloride. Tetrahedron. 1994, 50 (25),7543-7556.
- Gordon W. Rewcastle.; Hamish S. Sutherland.; Claudette A. Weir.; Adrian G. Blackburn.; William A. Denny. An improved synthesis of isonitrosoacetanilides. Tetrahedron Lett. 2005, 46 (50),8719-8721.