N-Hydroxysulfosuccinimide sodium salt, 97%
N-Hydroxysulfosuccinimide sodium salt, 97%
N-Hydroxysulfosuccinimide sodium salt, 97%
Thermo Scientific Chemicals

N-Hydroxysulfosuccinimide sodium salt, 97%

CAS: 106627-54-7 | C4H4NNaO6S | 217.127 g/mol
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Quantity:
250 mg
5 g
Catalog number H52795.MD
also known as H52795-MD
Price (TWD)
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Quantity:
250 mg
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Chemical Identifiers
CAS106627-54-7
IUPAC Namesodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
Molecular FormulaC4H4NNaO6S
InChI KeyRPENMORRBUTCPR-UHFFFAOYNA-M
SMILES[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to pale cream or pale yellow
FormPowder
Assay (unspecified)≥96.0%
N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

Solubility
Soluble in methanol and water.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Neves, M. M. P. S.; González-García, M. B.; Hernández-Santos, D.; Fanjul-Bolado, P. Streptavidin functionalized nickel nanowires: A new ferromagnetic platform for biotinylated-based assays. Talanta 2015, 144, 283-288.
  2. Huang, X.; Xu, Z.; Mao, Y.; Ji, Y.; Xu, H.; Xiong, Y.; Li, Y. Gold nanoparticle-based dynamic light scattering immunoassay for ultrasensitive detection of Listeria monocytogenes in lettuces. Biosens. Bioelectron. 2015, 66, 184-190.s