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N-Fmoc-1-trityl-L-histidine, 98%
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N-Fmoc-1-trityl-L-histidine, 98%
N-Fmoc-1-trityl-L-histidine, 98%
N-Fmoc-1-trityl-L-histidine, 98%
Thermo Scientific Chemicals

N-Fmoc-1-trityl-L-histidine, 98%

CAS: 109425-51-6 | C40H33N3O4 | 619.721 g/mol
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Catalog number H59711.06
also known as H59711-06
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Chemical Identifiers
CAS109425-51-6
IUPAC Name2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoic acid
Molecular FormulaC40H33N3O4
InChI KeyXXMYDXUIZKNHDT-UHFFFAOYNA-N
SMILESOC(=O)C(CC1=CN(C=N1)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C12
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)97.5% min
It is used in the synthesis and application of Fmoc-His(3-Bum)-OH.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used in the synthesis and application of Fmoc-His(3-Bum)-OH.

Solubility
Slightly soluble in water.

Notes
Moisture sensitive. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from heat. Keep it refrigerated.
RUO – Research Use Only

General References:

  1. Peter Sieber, et al. Protection of histidine in peptide synthesis: A Reassessment of the trityl group.Tetrahedron Lett.,1987,28(48), 6031-6034.
  2. M. Mergler, et al. Synthesis and Application of Fmoc-His(3-Bum)-OH.Journal of Peptide Science.,2001,7(9), 502-510.