2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used as a derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum. Synthesis of organohydrazide chelate complexes of rhenium and technetium. Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
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Applications
2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used as a derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum. Synthesis of organohydrazide chelate complexes of rhenium and technetium. Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
Solubility
Soluble in aqueous acid.
Notes
Store in cool, dry place in tightly closed container. With good ventilation. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Yan Weng; Fang Xie; Li Xu; Dmitri Zagorevski; David C. Spink; Xinxin Ding; Yan Weng; Fang Xie; Li Xu; Dmitri Zagorevski; David C. Spink; Xinxin Ding. Analysis of testosterone and dihydrotestosterone in mouse tissues by liquid chromatography-electrospray ionization-tandem mass spectrometry. Analytical Biochemistry. 2010, 402(2), 121-128.
- Hirsch-Kuchma M, et al. The synthesis and characterization of technetium and rhenium hydrazinopyrimidine chelate complexes. J. Chem. Soc., Dalton Trans. 1997, 183185-88.