1-Aminocyclobutanecarboxylic acid, 95%
1-Aminocyclobutanecarboxylic acid, 95%
1-Aminocyclobutanecarboxylic acid, 95%
Thermo Scientific Chemicals

1-Aminocyclobutanecarboxylic acid, 95%

CAS: 22264-50-2 | C5H9NO2 | 115.132 g/mol
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1 g
5 g
Catalog number H64459.03
also known as H64459-03
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1 g
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Chemical Identifiers
CAS22264-50-2
IUPAC Name1-aminocyclobutane-1-carboxylic acid
Molecular FormulaC5H9NO2
InChI KeyFVTVMQPGKVHSEY-UHFFFAOYSA-N
SMILESNC1(CCC1)C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to cream
FormPowder or crystalline powder
Assay≥94.0%
Assay (unspecified)≥94.0%
ACBC is an NMDA receptor antagonist acting at the glycine site. It acts as an agonist being an analog of glycine at the NMDA-glycine receptor site. This affects the signal transmission in the CNS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
ACBC is an NMDA receptor antagonist acting at the glycine site. It acts as an agonist being an analog of glycine at the NMDA-glycine receptor site. This affects the signal transmission in the CNS.

Solubility
Soluble to 100 mM in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. George W. Kabalka, et al. Synthesis of a novel boronated 1-aminocyclobutanecarboxylic acid as a potential boron neutron capture therapy agent.Appl. Organomet. Chem.,2003,17(6-7), 398-402.
  2. Eytan Gershonov, et al. 1-Aminocyclobutanecarboxylic Acid Derivatives as Novel Structural Elements in Bioactive Peptides: Application to Tuftsin Analogs.J. Med. Chem.,1996,39(24), 4833-4843.