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Carbenoxolone disodium salt, 97+%
CAS: 7421-40-1 | C34H48Na2O7 | 614.73 g/mol
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Chemical Identifiers
CAS7421-40-1
IUPAC Namedisodium (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-[(3-carboxylatopropanoyl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate
Molecular FormulaC34H48Na2O7
InChI KeyBQENDLAVTKRQMS-SBBGFIFASA-L
SMILES[Na+].[Na+].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CCC([O-])=O)C(C)(C)[C@]3([H])CC[C@@]12C)C([O-])=O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to pale cream
Assay from Supplier's CofA≥97.0%
FormPowder
Carbenoxolone is anti-inflammatory. It is often used as a gap junction inhibitor in neuroscience research. Carbenoxolone is also an inhibitor of the steroid dehydrogenase enzymes 11 β-hydroxysteroid dehydrogenase (human) and 3α, 20 β-hydroxysteroid dehydrogenase (bacterial). It is used for the treatment of digestive tract ulcers, especially in the stomach. Used in the treatment of peptic, mainly gastric, ulcers. It is often used as a gap junction inhibitor in neuroscience research.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water to 100 mM.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.
Soluble in water to 100 mM.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.
RUO – Research Use Only
General References:
- L. Horwich,; R. Galloway.Treatment of gastric ulceration with carbenoxolone sodium: clinical and radiological evaluation.. Br Med J. 1965 , 2 (5473), 1274-1277..
- W. Hausmann,; A. L. Tarnoky. Biochemical Effects Of Short-Term Treatment With Carbenoxolone Disodium. British Journal of Pharmacology and Chemotherapy. 1966, 26 (2) , 412-420.