Chlorpropamide
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Chlorpropamide
Chlorpropamide
Chlorpropamide
Thermo Scientific Chemicals

Chlorpropamide

Increases insulin secretion | CAS: 94-20-2 | C10H13ClN2O3S | 276.735 g/mol
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Catalog number J64110.14
also known as J64110-14
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Chemical Identifiers
CAS94-20-2
IUPAC Name1-(4-chlorobenzenesulfonyl)-3-propylurea
Molecular FormulaC10H13ClN2O3S
InChI KeyRKWGIWYCVPQPMF-UHFFFAOYSA-N
SMILESCCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to beige
FormPowder or crystalline powder
Assay≥98.0% (HPLC)
Chlorpropamide is used in the treatment of diabetes metilus type 2. It acts to increase the secretion of insulin and is not effective in patients who do not have pancreatic beta cell function.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chlorpropamide is used in the treatment of diabetes metilus type 2. It acts to increase the secretion of insulin and is not effective in patients who do not have pancreatic beta cell function.

Solubility
Soluble in ethanol (1:12), acetone (1:5), chloroform (1:9) and solutions of alkali hydroxides. Does not mix well with water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Arnold M.Moses; Patricia Numann ; Myron Miller. Mechanism of chlorpropamide-induced antidiuresis in man: Evidence for release of ADH and enhancement of peripheral action. Metabolism. 1973, 22,(1), 59-66.
  2. R.D.Leslie; D.A.Pyke. Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. Br Med J. 1978, 2,(6151), 1519-1521.